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BC6005 > Commonly Employed Approaches For Cancer Gene Therapy > Flashcards

Commonly Employed Approaches For Cancer Gene Therapy Flashcards

1
Q

Introduction of cytokine genes into cancer cells…

A
  1. Provokes localised inflammatory response
  2. Initiates anti-tumour cell immune response
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2
Q

Mutated tumor suppressor genes (p53, APC)

A

Delivery of p53 or APC to restore lost suppressor function

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3
Q

Protection of haemopoietic stem cells from toxic effects of chemotherapeutic agents by…

A

Insertion of a drug resistance gene
eg. multi-drug resistance gene (mdr-1) KO of drug target

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BC6005 (22 decks)

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