Antibodies Flashcards
1
Q
Almost all monoclonic antibodies produced as drugs are based on…
A
The IgG format
2
Q
IgA is located…
A
Predominantly in the intestinal tract
3
Q
IgM make up about…
A
6-10% of Ig pool
4
Q
IgD are found…
A
On the surface of B cells
5
Q
IgE respond to…
A
Respond to parasitic worms and allergens e.g. pollen
6
Q
Immune Diversity is created by…
A
V-D-J recombination of the heavy chain gene (IGH)
7
Q
Switching Ig class can happen through…
A
Recombination of constant regions
8
Q
The […] and […] or light chains, can undergo […]
A
Kappa; lambda; V-J recombination
