Colorectal cancer

Question 1

Name 2 genetic risk factors?

Answer 1

1. Familial adenomatous polyps

2. Heriditary non polyposis colorectal cancer

Question 2

Describe the features of HNPCC?

Answer 2

1. autosomal dominant
2. most common form of inherited colon cancer
3. increases risk of endometrial cancer

Question 3

Describe the features of FAP?

Answer 3

1. rare autosomal dominant condition
2. due to mutation in tumor supressor APC
3. leads to hundered of polyps in the colon

Question 4

Where is colorectal cancer most commonly found?

Answer 4

1. Rectal (40%)

2. Sigmoid (30%)

Question 5

Name 3 risk factors of Colorectal cancer?

Answer 5

1. Polyps
2. Ulcerative colitis
3. low fibre diet

Question 6

What are the main clinical features of right-sided Colorectal cancer?

Answer 6

1. iron deficiency anaemia
2. weight loss
3. palpable mass

Question 7

What are the main clinical features of left sided colorectal cancer?

Answer 7

1. Rectal bleeding
2. Altered bowel habits
   3, Obstruction