Colorectal Cancer Flashcards

1
Q

Colorectal Cancer Types

A

Mostly Adenocarcinoma
2/3 Colonic
1/3 Rectal

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2
Q

How common is Colorectal Cancer?

A

2nd most common

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3
Q

Risk Factors for Colorectal Cancer: SIIN

A
Sporadic 95%
Inheritable:
HNPCC 5%, FAP <1%
Inflammatory Bowel Disease
Neoplastic Polyps
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4
Q

Risk Factors for Sporadic CC:

A
Male 
Age
Increasing 
Previous Cancer
Environmental 
- Diet
- Obesity 
- Smoke
- Exercise
- Diabetes
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5
Q

Metastasis of Colorectal Cancer

A

Lung
Liver
Lymphatics
Bone

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6
Q

Colorectal Cancer Symptoms

A
Rectal Bleeding 
Altered Bowel Opening - diarrhoea
Abdominal Pain 
Anorexia
Weight Loss
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7
Q

Age - Colorectal Cancer

A

86% of presentations are in those > 60 years

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8
Q

Right sided Colorectal Cancer

A
Weakness
Weight loss
Vague pain
Obstruction 
Anaemia
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9
Q

Left sided Colorectal Cancer

A

Altered bowel habit
Fresh blood
Mucus
Obstruction

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10
Q

Signs Colorectal Cancer

A

Palpable Rectal Mass
Abdominal Mass
Anaemic

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11
Q

Investigations Colorectal Cancer

A
Colonoscopy with biopsy
CT
CT Colonography 
Barium Enema 
Bloods - FIT, FBC, LFT
Liver US (mets) 
Sigmoidoscopy 
MRI
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12
Q

Colorectal Cancer Screening

A

50-74 yrs
Every 2 years
FIT Testing
Especially - px with Heritable cx risk (FAP, HNPCC, IBD, PHcx, FHcx)

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13
Q

Colorectal Cancer Treatment SRC

A
  • Surgery
    Laparoscopic (tumour removal
    Endoscopic, Colostomy (for stoma opening)
    Partial Hepatectomy (treat metastases). - Radiotherapy (Palliation) (in Rectal Cancer)
  • Chemotherapy (Adjuvant) (After surgery)
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