Colorectal Cancer Flashcards
Colorectal Cancer Types
Mostly Adenocarcinoma
2/3 Colonic
1/3 Rectal
How common is Colorectal Cancer?
2nd most common
Risk Factors for Colorectal Cancer: SIIN
Sporadic 95% Inheritable: HNPCC 5%, FAP <1% Inflammatory Bowel Disease Neoplastic Polyps
Risk Factors for Sporadic CC:
Male Age Increasing Previous Cancer Environmental - Diet - Obesity - Smoke - Exercise - Diabetes
Metastasis of Colorectal Cancer
Lung
Liver
Lymphatics
Bone
Colorectal Cancer Symptoms
Rectal Bleeding Altered Bowel Opening - diarrhoea Abdominal Pain Anorexia Weight Loss
Age - Colorectal Cancer
86% of presentations are in those > 60 years
Right sided Colorectal Cancer
Weakness Weight loss Vague pain Obstruction Anaemia
Left sided Colorectal Cancer
Altered bowel habit
Fresh blood
Mucus
Obstruction
Signs Colorectal Cancer
Palpable Rectal Mass
Abdominal Mass
Anaemic
Investigations Colorectal Cancer
Colonoscopy with biopsy CT CT Colonography Barium Enema Bloods - FIT, FBC, LFT Liver US (mets) Sigmoidoscopy MRI
Colorectal Cancer Screening
50-74 yrs
Every 2 years
FIT Testing
Especially - px with Heritable cx risk (FAP, HNPCC, IBD, PHcx, FHcx)
Colorectal Cancer Treatment SRC
- Surgery
Laparoscopic (tumour removal
Endoscopic, Colostomy (for stoma opening)
Partial Hepatectomy (treat metastases). - Radiotherapy (Palliation) (in Rectal Cancer) - Chemotherapy (Adjuvant) (After surgery)