Cognitive Pt 1 Flashcards

1
Q

Difference in onset btw delirium and dementia

A

Delirium – rapid onset, specific cause (infection, medication) PREVENTABLE, short duration
Dementia - progressive, longer duration, and not preventable

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2
Q

Drugs linked to delirium

A

psychoactive agents, narcotics, anticholinergics

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3
Q

True or False
Depression commonly occurs with Alzheimer’s disease

A

True

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4
Q

Depression and Dementia similar features

A

apathy
loss of interest in activities
social withdrawal
isolation
trouble concentrating
impaired thinking

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5
Q

What is a risk factor for dementia

A

= depression
decreased cognitive reserve and anti-depressants may contribute

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6
Q

Amnestic dementia example and what it involves

A

memory loss
example: Alzheimer’s

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7
Q

Non amnestic example and what it involves

A

NO memory loss
example: Lewy Body Dementia

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8
Q

Vascular Dementia clinical symptoms ( 3)

A
  • Impaired attention, planning
  • Difficulties with complex activities
  • Disorganized thought
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9
Q

Vascular dementia 2 common traits

A
  1. apathy
  2. mood changes
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10
Q

5 hallmark signs of Lewy Body dementia

A
  1. Complex visual hallucinations
  2. Parkinsonism
  3. Sleep disturbances
  4. Autonomic symptoms (i.e., hypotension)
  5. Fluctuating cognition
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11
Q

Vascular Dementia may occur with —–

A

alzheimer’s

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12
Q

Lewy Body Dementia may occur with ——

A

Parkinson’s disease

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13
Q

Frontotemporal dementia 4 characteristics

A
  1. younger ( 50 to 60 years old)
  2. memory intact ( early age)
  3. changes in behavior + personality
  4. Impulsiveness
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14
Q

Alzheimer’s disease 2 characteristics

A
  1. Gradual loss of memory and function leading to total dependence on caregivers
  2. Eventual inability to recognize family/friends/self
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15
Q

when do neurobiological changes occur with dementia

A

years before the onset

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16
Q

What markers are elevated in pre dementia ? dementia?

A

Predementia: elevated amyloid markers
Dementia: structural changes

17
Q

3 diagnostic markers for Alzheimer’s disease

A
  1. medial temporal atrophy
  2. Temperoparietal hypometabolism
  3. abnormal markers ( tau proteins)
18
Q

Which areas of the brain are most affected by dementia, specifically AD?

A

Memory and language

19
Q

What is APOE and why is it important?

A

biomarker that is linked to gain in function

20
Q

Which APOE is at highest risk for alzheimer’s ? lowest?

A

APOE 4: highest risk for alzheimer’s
APOE 2: lowest risk for alzheimer’s

21
Q

Is there a cure for dementia?

A

No cure- can only attempt to delay progression
** catch in MCI stage can slow down process of dementia

22
Q

Aricept / donepezil side effects

A

GI issues

23
Q

Namenda / memantine side effects

A

falls