Co-amoxiclav Flashcards
1
Q
drug classification
A
broad spectrum antibiotic
type of penicillin beta lactam antibiotic
mix of clavulanic acid and amoxicillin
2
Q
used to treat
A
infections likely causes by amoxicillin resistant beta lactamase producing strains
influenzae, S.aureus
can treat gram positive and gram negative
3
Q
chemical structure
A
clavulanic acid
amoxicillin
4
Q
brand name
A
augmentin
clavulin
5
Q
bioavailability
A
64%
6
Q
mechanism of action
A
amoxicillin binds to transpeptidase which prevents PBPs from cross-linking with the D-ala-D-ala chain
cell lyses occur
clavulanic acid prevents b lactamases from breaking down amoxicillin by binding to it
7
Q
side effects for penicillins
A
d&V
nausea
skin reactions
hypersensitivity
thrombocytopenia