Co-amoxiclav Flashcards

1
Q

drug classification

A

broad spectrum antibiotic
type of penicillin beta lactam antibiotic
mix of clavulanic acid and amoxicillin

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2
Q

used to treat

A

infections likely causes by amoxicillin resistant beta lactamase producing strains

influenzae, S.aureus
can treat gram positive and gram negative

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3
Q

chemical structure

A

clavulanic acid
amoxicillin

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4
Q

brand name

A

augmentin
clavulin

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5
Q

bioavailability

A

64%

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6
Q

mechanism of action

A

amoxicillin binds to transpeptidase which prevents PBPs from cross-linking with the D-ala-D-ala chain
cell lyses occur
clavulanic acid prevents b lactamases from breaking down amoxicillin by binding to it

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7
Q

side effects for penicillins

A

d&V
nausea
skin reactions
hypersensitivity
thrombocytopenia

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