CNS infections Flashcards
Where do CNS infections arise?
contagious
trauma
haematogenous
via nerves
what is meningitis
inflammation of meninges
what is encephalitis
Inflammation of the brain substance
What is myelitis
Infection of the spinal cord
symptoms of meningitis
stiff neck
headache
vomit
drowsy
difference in viral meningitis and bacterial meningitis
Viral - benign - common
bacterial - more severe - less common
different types of bacterial meningitis
Neiseria meningitis
h influenza ( type B )
strep pneumoniae
What causes TB meningitis
M tuberculosis
diagnosis of fungal meningitis?
CSF examination (PCR) blood culture
Treatment of bacterial meningitis?
antibiotic therapy
if meningococcal - benzyl penicillin IV/IM
if unknown - cefotaxime/ ceftriaxone
Where does encephalitis come from?
Herpes simplex (HSV-1)
symptoms of rabies encephalitis?
muscles spasm
convulsions
pharyngeal spasm
What are prions?
Proteins which act as infectious agents
no immune response
normal proteins are folded to form abnormal proteins
what can prions lead to
Creutzfelt jakob disease
what type of process creates prions
autocatalytic process
