CNS Infections

Question 1

M/c organisms causing bacterial meningitis

Answer 1

Strept. Pneumonia
Neiserria meningitides

Question 2

Tx of bacterial meningitis

Answer 2

General:3rd generation cephalosporin;
If meningococcal: Penicillin G

Question 3

Tx of contacts for bacterial meningitis

Answer 3

Single does ciprofloxacin or rifampicin for the contacts

Question 4

Tx of brain abscess

Answer 4

Medical: empirical 3rd gen cephalosporin +
Metronidazole
Surgical: excision

Question 5

M/c organism causing viral Encephalitis

Answer 5

HSV

Question 6

Tx of viral Encephalitis

Answer 6

Antipyretics
Acyclovir or gancyclovir for 2 weeks
Antiepileptic drug

Question 7

M/c causative organism in acute septic meningitis in children

Answer 7

E. Coli and GBS

Question 8

M/C causative organism in acute septic meningitis in young adults

Answer 8

Neiserria meningitides

Question 9

M/C causative organism in chronic meningitis

Answer 9

Mycobacteria TB

Question 10

M/c causative organism causing acute septic meningitis in older adults

Answer 10

Strpt. Pneumonia

Question 11

M/C causative organism causing acute aseptic meningitis

Answer 11

Influenza, enterovirus, measles

Question 12

CSF findings:
Color: clear
Cells: normal- 1000
WBC: lymphocytes
CSF plasma glucose ratio: normal
Proteins: normal

What is the diagnosis?

Answer 12

Viral meningitis

Question 13

CSF findings
Color: turbid
Cells: >1000
WBC : neutrophils
Glucose: low
Proteins : >1 g/L

Answer 13

Bacterial meningitis

Question 14

CSF findings
Color : normal/turbid
Cells up to 1000
WBC: lymphocytes
Glucose normal/low
Proteins: up to 5

Diagnosis?

Answer 14

Fungal meningitis

Question 15

CSF findings
Color :clear/turbid slightly
Cells: increased
WBC: lymphocytes
Glucose :low
Proteins:normal or high

Answer 15

TB meningitis