CNS-FA17-Limbic System Flashcards

1
Q

The portion of nervous system that is responsible for mood, emotion, affective behavior (bonding) and memory?

A

Limbic system

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2
Q

T/F: Autism is believed to be a deficit in the limbic system

A

True

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3
Q

Structures associated with limbic system?

A

Parahippocampal gyri
Cingulatate gyri
EntoRhinal cortex
Hippocampal formation

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4
Q

The parahippocampus gyrus and cingulate together make up which lobe?

A

Limbic lobe

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5
Q

Cells a part of hippocampal formation?

A

Hippocampus proper

Subiculum

Dentate gyri

Fimbria

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6
Q

Portion of the hippocampal formation that contains pyramidal cells and is divided into CA1,2&3-Cornu of Ammon

A

Hippocampal proper

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7
Q

Transition zone between the parahippocampal gyrus and hippocampus is called

A

Subiculum

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8
Q

Nucleus/nucleus in the hippocampal formation that have neurons cells granule cells

A

Dentate gyrus

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9
Q

Fibers from hippocampal formation that will become the fornix?

A

Fimbria

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10
Q

Intrinsic connections:

Perforant pathway

A

Entorhinal cortex —> dentate gyrus —> through Mossy fibers (granule cell axon) —> CA3 —> from Pyramidal cells of CA3 —> form fimbria of formix

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11
Q

Collaterals fibers coming from the the alveus going to CA1

A

Schaffer collateral

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12
Q

Efferent connections of limbic system

A
  1. Entorhinal cortex to association cortex

2. Fornix to mamilary bodies

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13
Q

Afferent connections of the limbic system

A

Septal nucleus —> hippocampus

Locus ceruleus (in pons) —> hippocampus

Raphe nucleus (in reticular formation) —> hippocampus

Ventral regimental area (in midbrain) —> hippocampus

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14
Q

Neurotransmitter fo septal nucleus

A

Cholinergic -ACH

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15
Q

Neurotransmitter of locus ceruleus

A

Noradrenergic

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16
Q

Neurotransmitter of Raphe nucleus

A

5-HT (depression)- Serotonin

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17
Q

Ventral tegmental area neurotransmitter transmitter

A

Dopaminergic (schizophrenia)

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18
Q

Afferent connection that goes to spinal cord to relieve pain and also cortex

A

Reticular formation

19
Q

Two types of of memory

A

Declarative

Procedural

20
Q

Declarative memory characterized by

A

Renal of facts and experiences

21
Q

Procedural memory characterized by

A

Skill i.e. writing/ walking

22
Q

Memory is believed to work through long term potentiation which can be described as

A

High resting potential in the neurons involved

23
Q

Long term potentiation allows what to occur

A

Perservation of memory

Reinforce memory

Plasticity

24
Q

Term defined by neurons always making new connects, breaking old ones

A

Plasticity

25
Definition: loss of short term memory after the event of lesion in hippocampal formation
Anterograde amnesia
26
Memory can also be lost by blocking which neurotransmitter
Ach (from septal cells)
27
Memory is improved by increasing which neurotransmitter. Usually done by blocking enzymes that break it down
Ach
28
Who proposed a circuit to explain emotions in 1938
Papez
29
Papez circuit
Cingulate gyrus —> hippocampal formation —> mammillary body —> anterior thalamic nuclei —> cingulate gyrus
30
The filing system of memory
Basal forebrain
31
Function of the basal forebrain
Consolidates memory “Wake” state- keeps neurons active and responsive Prolongs responsiveness of cortical neurons
32
Pleasure center
Septal area
33
Afferent to septal area
Comes from: 1. Amygdala 2. Olfactory tract 3. Hippocampus 4. Brainstem
34
Septal area efferent goes to
Hypothalamus Brainstem Hippocampus
35
Septal area function
Reward area Memory via Ach production Slow wave activity of hippocampus
36
The gyrus has connections with: Amygdala and insula Amygdala and ortbitofrontal cortex Ventral striatum, putamen, and supplemental motor area
Cingulate gyrus
37
What receives input from the intralaminar nuclei and responds to pain
Cingulate gyrus
38
Two parts of amygdala
Dorsomedial Ventral lateral
39
Dorsomedial aspect of Amygdala receive input from
Afferent from olfactory cortex
40
Ventrolateral aspect of amygdala receives input from
Afferent from visual, auditory, hippocampus and somatosensory cortex
41
Both the mediodorsal and ventrolateral portion of are involved with
Defense vs Attack postures
42
Central functions of the amygdala
Posture (instinctive) Cognitive Endocrine Modulation of reticular formation
43
T/F: Amygdala is important for fear
True