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neuroanatomy > CNS-FA17-Limbic System > Flashcards

CNS-FA17-Limbic System Flashcards

1
Q

The portion of nervous system that is responsible for mood, emotion, affective behavior (bonding) and memory?

A

Limbic system

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2
Q

T/F: Autism is believed to be a deficit in the limbic system

A

True

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3
Q

Structures associated with limbic system?

A

Parahippocampal gyri
Cingulatate gyri
EntoRhinal cortex
Hippocampal formation

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4
Q

The parahippocampus gyrus and cingulate together make up which lobe?

A

Limbic lobe

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5
Q

Cells a part of hippocampal formation?

A

Hippocampus proper

Subiculum

Dentate gyri

Fimbria

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6
Q

Portion of the hippocampal formation that contains pyramidal cells and is divided into CA1,2&3-Cornu of Ammon

A

Hippocampal proper

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7
Q

Transition zone between the parahippocampal gyrus and hippocampus is called

A

Subiculum

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8
Q

Nucleus/nucleus in the hippocampal formation that have neurons cells granule cells

A

Dentate gyrus

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9
Q

Fibers from hippocampal formation that will become the fornix?

A

Fimbria

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10
Q

Intrinsic connections:

Perforant pathway

A

Entorhinal cortex —> dentate gyrus —> through Mossy fibers (granule cell axon) —> CA3 —> from Pyramidal cells of CA3 —> form fimbria of formix

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11
Q

Collaterals fibers coming from the the alveus going to CA1

A

Schaffer collateral

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12
Q

Efferent connections of limbic system

A
  1. Entorhinal cortex to association cortex

2. Fornix to mamilary bodies

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13
Q

Afferent connections of the limbic system

A

Septal nucleus —> hippocampus

Locus ceruleus (in pons) —> hippocampus

Raphe nucleus (in reticular formation) —> hippocampus

Ventral regimental area (in midbrain) —> hippocampus

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14
Q

Neurotransmitter fo septal nucleus

A

Cholinergic -ACH

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15
Q

Neurotransmitter of locus ceruleus

A

Noradrenergic

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16
Q

Neurotransmitter of Raphe nucleus

A

5-HT (depression)- Serotonin

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17
Q

Ventral tegmental area neurotransmitter transmitter

A

Dopaminergic (schizophrenia)

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18
Q

Afferent connection that goes to spinal cord to relieve pain and also cortex

A

Reticular formation

19
Q

Two types of of memory

A

Declarative

Procedural

20
Q

Declarative memory characterized by

A

Renal of facts and experiences

21
Q

Procedural memory characterized by

A

Skill i.e. writing/ walking

22
Q

Memory is believed to work through long term potentiation which can be described as

A

High resting potential in the neurons involved

23
Q

Long term potentiation allows what to occur

A

Perservation of memory

Reinforce memory

Plasticity

24
Q

Term defined by neurons always making new connects, breaking old ones

A

Plasticity

25
Q

Definition: loss of short term memory after the event of lesion in hippocampal formation

A

Anterograde amnesia

26
Q

Memory can also be lost by blocking which neurotransmitter

A

Ach (from septal cells)

27
Q

Memory is improved by increasing which neurotransmitter.

Usually done by blocking enzymes that break it down

A

Ach

28
Q

Who proposed a circuit to explain emotions in 1938

A

Papez

29
Q

Papez circuit

A

Cingulate gyrus —> hippocampal formation —> mammillary body —> anterior thalamic nuclei —> cingulate gyrus

30
Q

The filing system of memory

A

Basal forebrain

31
Q

Function of the basal forebrain

A

Consolidates memory

“Wake” state- keeps neurons active and responsive

Prolongs responsiveness of cortical neurons

32
Q

Pleasure center

A

Septal area

33
Q

Afferent to septal area

A

Comes from:

  1. Amygdala
  2. Olfactory tract
  3. Hippocampus
  4. Brainstem
34
Q

Septal area efferent goes to

A

Hypothalamus

Brainstem

Hippocampus

35
Q

Septal area function

A

Reward area

Memory via Ach production

Slow wave activity of hippocampus

36
Q

The gyrus has connections with:

Amygdala and insula

Amygdala and ortbitofrontal cortex

Ventral striatum, putamen, and supplemental motor area

A

Cingulate gyrus

37
Q

What receives input from the intralaminar nuclei and responds to pain

A

Cingulate gyrus

38
Q

Two parts of amygdala

A

Dorsomedial

Ventral lateral

39
Q

Dorsomedial aspect of Amygdala receive input from

A

Afferent from olfactory cortex

40
Q

Ventrolateral aspect of amygdala receives input from

A

Afferent from visual, auditory, hippocampus and somatosensory cortex

41
Q

Both the mediodorsal and ventrolateral portion of are involved with

A

Defense vs Attack postures

42
Q

Central functions of the amygdala

A

Posture (instinctive)

Cognitive

Endocrine

Modulation of reticular formation

43
Q

T/F: Amygdala is important for fear

A

True

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