CNS and PNS Flashcards

1
Q

UMN lesions (5)

A
  1. TBI
  2. CVA
  3. SCI
  4. MS
  5. Parkinson’s
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2
Q

Originates in anterior horn of SC and out into periphery. Skeletal mm. Cranial nerves. Efferent nerves

A

LMN

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3
Q

LMN lesions (4)

A
  1. Muscular dystrophy
  2. Polio
  3. Peripheral nerve injury
  4. Myasthenia gravis
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4
Q

Male genetic disorder. Proximal weakness first in pelvis then shoulder. Flexion contractures and scoliosis. Most severe

A

Duchenne Muscular Dystrophy DMD

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5
Q

Viral infection, induces flaccid weakness by damaging motor neurons. Don’t push too hard! Healing: motor units- mm hypertrophy- reinnervation

A

Post polio/poliomyelitis

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6
Q

Decreased comm b/t motor neuron and mm. Autoimmune common in females 20-30. Prox weakness (eyes, face) before distal (limbs)

A

Myasthenia Gravis

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7
Q

Temp paralysis and sensory loss. Peripheral nerve injury

A

Neuropraxia

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8
Q

Stretch or compression of axon. Peripheral nerve injury

A

Axonotmesis

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9
Q

Severed neuron. Peripheral nerve injury

A

Neuromesis

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10
Q

Neuromuscular disorders. (4)

A
  1. MS
  2. GBS
  3. ALS
  4. Parkinson’s
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11
Q

Chronic, slow progressing disease of CNS. Demylinated glial plaques of UMN. Etiology unknown

A

MS

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12
Q

Four types of MS

A
  1. Benign
  2. Exacerbating-Remitting
  3. Remitting-Progressive
  4. Progressive
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13
Q

MS w/ Abrupt onset. Almost complete remission. Little to no permanent functional disability

A

Benign MS

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14
Q

MS w/ sudden onset. Partial or complete remission. Remain stable for long periods of time

A

Exacerbating-Remitting MS

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15
Q

MS w/ gradual onset and potential for sudden symptoms in one area. Exacerbations expected. Progressive disability. Symptoms do not remit as completely.

A

Remitting-Progressive MS

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16
Q

MS w/ slow onset. Exacerbations. No remitting of symptoms resulting in severe disability. More common in men

A

Progressive

17
Q

MS symptoms (4)

A
  1. Motor function loss
  2. Fatigue
  3. Spasticity
  4. Incontinence
18
Q

Spasticity due to MS results from…

A

corticospinal demyelination

19
Q

MS. Slow, uncoordinated progression of reciprocal LE movements. Staggering, wide base gait, poor footing

A

Ataxia

20
Q

MS. Inability to perform rapidly alternating movements

A

Dysdiadochokinesia

21
Q

MS. Overreaching

A

Dysmetria

22
Q

MS optic defects (3)

A
  1. Diplopia
  2. Optic neuritis
  3. Nystagmus
23
Q

MS speech (3)

A
  1. Slurring
  2. Dysphagia
  3. Dysarthria
24
Q

MS functional rehab (5)

A
  1. Bed mob
  2. Balance
  3. Amb
  4. Xfers
  5. Energy conservation
25
Q

MS precautions (3)

A
  1. Overstretching
  2. Heat
  3. Mm fatigue
26
Q

Chronic progressive degenerative disease where rate of dopamine produced drops. Idiopathic onset.

A

Parkinson’s

27
Q

Parkinson’s ACh>Dopamine=

A

Facilitation>inhibition

28
Q

Parkinson’s affects _______ which is outside the corticospinal tract

A

Extrapyramidal (EP) system

29
Q

EP system regulates (3)

A
  1. Posture
  2. Righting reactions
  3. Initiate movement
30
Q

Parkinson’s s/s (4)

A
  1. Tremors
  2. Rigidity
  3. Postural reflex loss
  4. Bradykinesia
31
Q

Parkinson’s rehab

A

controlled mobility w/ rotation

32
Q

Both UMN and LMN. Degeneration of motor cells in frontal cortex, parietal lobe, cranial nerve nuclei, and anterior horn. Male more common

A

ALS

33
Q

Two tracts most affected by ALS

A

Corticospinal and corticobulbar

34
Q

ALS symptoms occur ______ first

A

Distally

35
Q

ALS rehab focus (5)

A
  1. ADs
  2. Low rep
  3. Xfer
  4. Deep breathing
  5. Shoulder mobs
36
Q

Acute, demyelination of cranial and spinal nerves. Re-myelination typically occurs. Attacks spinal and cranial roots

A

GBS

37
Q

GBS s/s (2)

A
  1. Symmetrical distal-prox weakness

2. Proprioceptive loss> sensory

38
Q

GBS acute rehab (2)

A
  1. Respiration

2. Maintain ROM

39
Q

GBS subacute rehab

A

PNF Iso-ecc-conc