CNS and PNS Flashcards
UMN lesions (5)
- TBI
- CVA
- SCI
- MS
- Parkinson’s
Originates in anterior horn of SC and out into periphery. Skeletal mm. Cranial nerves. Efferent nerves
LMN
LMN lesions (4)
- Muscular dystrophy
- Polio
- Peripheral nerve injury
- Myasthenia gravis
Male genetic disorder. Proximal weakness first in pelvis then shoulder. Flexion contractures and scoliosis. Most severe
Duchenne Muscular Dystrophy DMD
Viral infection, induces flaccid weakness by damaging motor neurons. Don’t push too hard! Healing: motor units- mm hypertrophy- reinnervation
Post polio/poliomyelitis
Decreased comm b/t motor neuron and mm. Autoimmune common in females 20-30. Prox weakness (eyes, face) before distal (limbs)
Myasthenia Gravis
Temp paralysis and sensory loss. Peripheral nerve injury
Neuropraxia
Stretch or compression of axon. Peripheral nerve injury
Axonotmesis
Severed neuron. Peripheral nerve injury
Neuromesis
Neuromuscular disorders. (4)
- MS
- GBS
- ALS
- Parkinson’s
Chronic, slow progressing disease of CNS. Demylinated glial plaques of UMN. Etiology unknown
MS
Four types of MS
- Benign
- Exacerbating-Remitting
- Remitting-Progressive
- Progressive
MS w/ Abrupt onset. Almost complete remission. Little to no permanent functional disability
Benign MS
MS w/ sudden onset. Partial or complete remission. Remain stable for long periods of time
Exacerbating-Remitting MS
MS w/ gradual onset and potential for sudden symptoms in one area. Exacerbations expected. Progressive disability. Symptoms do not remit as completely.
Remitting-Progressive MS