CNS Flashcards
Functions of the nervous system
- Sensory input – gathering information
Sensory Receptors monitor changes, called stimuli - Integration – Processes and interprets sensory input
- Motor output – a response or effect, activates muscles or glands
Organisation of the nervous system
- Structures (structural classification)
2. Activities (functional classification)
Two structural classfications of the nervous system are?
- Central Nervous System (CNS)
2. Peripheral Nervous System (PNS)
Organs and functions of CNS
Organs – Brain and spinal cord
Functions - ▪ Integration; command center
▪ Interprets incoming sensory information
▪ Issues outgoing instructions
Organs and functions of PNS
Nerves extending from the brain and spinal cord
Spinal nerves – carry impulses to and from the spinal cord
Cranial Nerves – Carry impulses to and from the brain
Functions – Serve as communication lines among sensory organs, the brain and spinal cord and glands or muscles
Functional classifications of PNS
- Sensory – sense organs
2. Motor – somatic/voluntary (skeletal muscles) and autonomic/involuntary (cardiac and smooth muscle)
2 principal Nervous tissue cell types
Neurons Supporting cells (Neuroglia)
What are the four types of Glial cells
Astrocytes
Microglial
Ependymal
Oligodendrocytes
Explain features of Astrocytes
- Most abundant and versatile neuroglia
- Positioned between neurons and capillary
- Link nutrient supply in capillaries to neurons and control chemical environment from any harmful substances in the blood.
Explain features of Microglial Cells
Spider like phagocytes that monitor the health of nearby neurons and remove debris like dead bone cells and bacteria
Explain features of Ependymal cells
Line the central cavities of the brain and spinal cord. The cilia maintains cerebrospinal fluid which fills the cavities and forms a watery cushion.
Explain features of Oligodendrocytes cells
▪ Wrap around nerve fibers in the central nervous system
▪ Produce myelin sheaths
Major regions of the Neuron
- Cell body -nucleus and metabolic centre of the cell
- Processes – fibres that extend from the cell body
Components of neuron cell body
▪ Cell body is the metabolic center of the neuron
▪ Nucleus with large nucleolus
▪ Nissl bodies
Rough endoplasmic reticulum
▪ Neurofibrils
Intermediate filaments that maintain cell shape
Components of the neuron processes
Dendrites – conduct impulses toward the cell body (100s)
Axons—conduct impulses away from the cell body ▪ End in axon terminals, which contain vesicles with neurotransmitters
Axon hillock – where axons start
Synaptic cleft—gap between axon terminals and the next neuron
Synapse—functional junction between nerves where a nerve impulse is transmitted
What is Myelin
White, fatty material covering axons ▪ Protects and insulates fibers ▪ Speeds nerve impulse transmission
What is myelin sheaths
Oligodendrocytes—produce myelin sheaths around axons of the CNS ▪ Lack a neurilemma
What are the 3 functional classifications of neurons?
- Sensory Afferent neurons
- Motor efferent neurons
- interneurons
What are the 3 structural classification of neurons and there features?
Multipolar neurons—many extensions from the cell body ▪ All motor and interneurons are multipolar ▪ Most common structural type
Bipolar neurons—one axon and one dendrite ▪ Located in special sense organs, such as nose and eye ▪ Rare in adults
Unipolar neurons—have a short single process leaving the cell body ▪ Sensory neurons found in PNS ganglia ▪ Conduct impulses both toward and away from the cell body
Describe actions of a sensory neuron
▪ Carry impulses from the sensory receptors to the CNS. Cell body is located in ganglion
▪ Receptors include: Dendrites have specific receptors that sense changes nearby ▪ Cutaneous sense organs in skin ▪ Proprioceptors in muscles and tendons
Describe actions of a motor neuron
Carry impulses from the central nervous system to viscera and/or muscles and glands. Cell bodies found within the central nervous system
Describe actions of an Interneurons
Cell bodies located in the CNS ▪ Connect sensory and motor neurons
Action Potential Steps
- The plasma membrane at rest is inactive (polarized- -70 mV). Fewer positive inside than outside. As long as the inside of the membrane is more negative (fewer positive ions) than the outside, the cell remains inactive
- Action potential = nerve impulse. ▪ A graded potential (localized depolarization) exists where the inside of the membrane is more positive and the outside is less positive ▪ If the stimulus is strong enough and sodium influx great enough, local depolarization activates the neuron to conduct an action potential (nerve impulse)
- ▪ If enough sodium enters the cell, the action potential (nerve impulse) starts and is propagated over the entire axon ▪ All-or-none response means the nerve impulse either is propagated or is not ▪ Fibers with myelin sheaths conduct nerve impulses more quickly. Reaches 30mV
- ▪ Membrane permeability changes again—becoming impermeable to sodium ions and permeable to potassium ions ▪ Potassium ions rapidly diffuse out of the neuron, repolarizing the membrane ▪ Repolarization involves restoring the inside of the membrane to a negative charge and the outer surface to a positive charge. Less than -70mV. hyperpolerization
- ▪ Initial conditions of sodium and potassium ions are restored using the sodium-potassium pump ▪ This pump, using ATP, restores the original configuration ▪ Three sodium ions are ejected from the cell while two potassium ions are returned to the cell ▪ Until repolarization is complete, a neuron cannot conduct another nerve impulse. Goes back to -70 mV
What is reflex and a reflex arc?
Rapid, predictable and involuntary responses to stimuli
Occur over neural pathways called reflex arcs