Clostridium Tetani Flashcards

1
Q

Características

A

Esporas terminales
Sensible al oxigeno
Tetanolisina
Tetanoespasmina
Inmunidad por vacunación muy efectiva

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2
Q

Hemolisina

A

Tetanolisina

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3
Q

Neurotoxina irreversible

A

Tetanoespasmina

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4
Q

Tetanoespasmina

A

Unión irreversible en la sinapsis
Codifica en un plasmado
Excitador sináptico
Parálisis espastica

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5
Q

Vacuna

A

Toxoides tetánico

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6
Q

Enfermedad

A

Tétanos

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7
Q

Tétanos

A
  1. Generalizado: contracción sostenida de músculos dorsales. Trismos masetero opistotonos. Mortalidad 30-50%
  2. Localizado: sx en una extremidad
  3. Neonatal: mortalidad >90%. Acortamientos de tejido umbilical con tijeras no estériles
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8
Q

Tx

A

Desbridamiento
Metronidazol
Inmunoglobulina
Vacuna

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