Clostridium Flashcards
Describe the habitat of clostridium
soil, mud , water, gut
Describe the morphology of clostridium
7-10 micrometer rod
All clostridium Bb are flagellated T/F
F all except C.perfr.
Clostridium are spore forming Bb T/F
T
Describe the oxidation fermentation test
test about carbohydrate metabolism
What does the OF test differentiate
Whether or nor the Bb use oxidative or fermentative metabolism
The spore in Clostridium is central as in B.anthracis T/F
F the spore is terminal or subterminal
Clostridium is a capsulated Bb T/F
F only C.perfringens is capsulated
What could destroy a clostridium spore
boiling for 3-4h in case of C.botulinum spore
Clostridium stain how?
Gram +
Does Clostridium propagate in anaerobic conditions
yes
All Clostridium can’t tolerate Oxy T/F
F the oxygen tolerance varies
What is the opt. temp. for Clostr.
37°c
Catalase oxidase
C - , O-
OF test
fermentative
Clostridium species produce several exotoxins name them
- alpha - lethal, necrotic, lecitinase
- beta - lethal, necrotic
- epsilon - lethal, necrotic
- iota - letha, necrotic
What agar can Clostridium be cultured on
-nutrient & blood agar
Name the Species that can cause malignant oedema (gas gangrenic diseases)
- C. septicum
- C.novyi
- C.haemolyticum
- C.histolyticum
- C.sordelli
Whcih Bb causes black leg in Ru,Ov
C. chauvoei
Whcih Bb causes human gas gangrene
C.perfringens A , C. novoyi A
Name the species which can cause enterotoxaemic diseases
- C. perfringens A,B,C,D
- C. colinum
Which Bb causes necrotic enteritis of chicken
C.perfringens A/C
Which Bb causes lamb dysentery
C. perfringens B
Which Bb causes chronic enteritis of pigs
C. perfringens C
Which Bb causes struck of Ov
C. perfringens C
Which Bb causes pulpy kindey disease of Ov
C. perfringens D
Which Bb causes ulcerative enteritis of Chicken
C.colinum
Which Bb causes tetanus
C.tetani
Which Bb causes botulism
C. botulinum
Describe the disease tetanus
is an infection characterized by muscle spasms
Other symptoms may include fever, sweating, headache, trouble swallowing, high blood pressure, and a fast heart rate
on what to culture C.septicum
nutrient agar
What diseases can C.novoyi cause
gas gangrene, infectious hepatitis in sheep, cattle
What diseases does C.haemolyticum cause
bacillary haemoglobinuria in cattle and sheep
Which C. can tolerate O2
C.histolyticum and C.botulinum
what does C.chauvoei have to be cultured on
blood agar
What is unique about C. perfringens
opt. temp: 40-45°c
no flagella
capsullated
What does C.colinum cause in quail, chicken, turkey
ulcerative enteritis
Which species does C.difficile affect
Dogy, horses, humans
Name the diseases of C. difficile
Ho: pseudomembranosus colitis
Ca: chronic diarrhoea
Eq: enterocolitis in newborn foals
How many serotypes does C.tetani have
10
What toxins does C.tetani release
neurotoxins
Which species are the most susceptible to C.tetani
ho, eq
How many toxin types does C.botulinum have
A-G
Which Bb causes Tyzzers disease
C.piliforme
What causes lethal enteritis in Rabbit
C.spiroforme
What does C. spiroforme look like
atypical coiled morphology
