Clinical Sciences Flashcards
Positive predictive value calculation
true positives / (true positives + false positives)
Sensitivity calculation
true pos / ( true pos + false neg)
Specificity calculation
true negative / (true neg + false pos)
Negative predictive value calculation
True neg / ( FN + TN)
Likelihood ratio for a positive test result calculation
sensitivity / (1-specificity)
Likelihood ratio for a negative test result calculation
(1-sensitivity) / specificity
ABL gene function, disease
Cytoplasmic tyrosine kinase
CML
C-myc function, disease
Transcription factor
Burkitt’s lymphoma
N-myc function, disease
Transcription factor
Neuroblastoma
BCL2 function, disease
Apoptosis regulator protein
Follicular lymphoma
RET function, disease
Tyrosine kinase receptor
MEN type II
RAS function, disease
G protein
Many cancers, esp panc
Erb-B2 (HER2-neu) function, disease
Tyrosine kinase receptor
Breast and ovarian
