Clinical Pathology --> Divalent cations

Question 1

What are the different mineral functions associated with C, P, and Mg?

Answer 1

1) Nerve function
2) Bone matrix
3) Blood clotting
4) Cellular metabolism
5) Muscle

Question 2

What does PTH do and where does it come from?

Answer 2

• PTh comes from the parathyroid gland and it gets released in reesponse to hypocalcemia and decreased Vitamin D
• PTH has the following fucntions:
• 1) Increases calcium and phosphorses reabsorption from the bone
• 2) Decreased phosphorous reabsorption by the kidneys
• 3) Increases activity of vitamin D
• ## 4) Increases calcium absorption from the gut and distal renal tubules

Question 3

Whatr does PTH related protein do?

Answer 3

• Maintains calcium balance in the fetus but it is NOT normally active in adults

Question 4

What does calcitonin do?

Answer 4

produced by thyroid parafollicular cells in response to hypercalcemia
- it functions to decrease serum calcium and phosphorous

Question 5

What does vitamin D do? Whats another name for it?

Answer 5

• another name for it is calcitrol and this is the metabolically active form of vitamin D
• it functions to increase serum calciumn and phosphorous

Question 6

what is free ionized calcium?

Answer 6

• its the biologically actuive fomr of calciu, its hormone regulated
• its 50% of the total calcium