Clinical - Disorders of Water Balance Flashcards
What controls body water
Thirst
Vasopressin
Renal medullary concentration of urine
What is the first process in evaluating hyponatremia
Measure serum osmolality
What causes isosmotic hyponatremia
Isotonic infusions of glucose, mannitol, or glycine
HyperTG, hyperproteinemia
What causes hyperosmotic hyponatremia
Hypertonic infusions of glucose, mannitol, or glycine
Sever hyperglycemia
What is the workup for hyposmotic hypovolemic hyponatremia
Measure urine osmolality and Na concentration
What is the workup for hyposmotic hypervolemic hyponatremia
Measure urine osmolality and Na concentration
What is the workup for hyposmotic euvolemic hyponatremia
Measure cortisol and thyrotropin levels, urinary Na, and urine osmolality
What is the cause of hyposmotic hypovolemic hyponatremia
Volume depletion, thiazide diuretics, adrenal insufficiency
What is the cause of hyposmotic hypervolemic hyponatremia
Edematous state and renal failure
What is the cause of hyposmotic euvolemic hyponatremia
Hypothyrodism, Addison disease, SIADH
What are the lab findings in SIADH
Low concentrations of serum uric acid, serum creatinine, and serum urea nitrogen
What is the most serious causes of SIADH
Small cell carcinoma of the lungs
CNS disorders, drugs
What is the treatment for hypovolemic hyponatremia with symptoms
Hypertonic saline
What is the treatment for hypovolemic hyponatremia without symptoms
Isotonic saline
What is the treatment for hypervolemic hyponatremia
Diuretics and aquaretics
water restriction and furosemide diuretics