Clinical - Diabetes and Ion Balance Flashcards
1
Q
What is central diabetes insipidus
A
Absence of circulating vasopressin due to destruction of the pituitary or congenital causes
2
Q
What is nephrogenic diabetes insipidus
A
Resistance of the renal collecting duct cell to the actions of vasopressin
3
Q
What three drugs may induce nephrogenic diabetes insipidus
A
Lithium
Demeclocycline
Amphotericin B
4
Q
What electrolyte abnormality may induce nephrogenic diabetes
A
Hypercalcemia
Hypokalemia
5
Q
What is the serum sodium in diabetes insipidus compared to primary polydipsia
A
Diabetes - high-normal or increased
Polydipsia - low-normal or low
6
Q
What sign implies volume depletion
A
Orthostatic hypotension
7
Q
What sign implies volume excess
A
Edema
8
Q
What are the symptoms of hypokalemia
A
Weakness, ileus, polyuria, rhabdomyolysis
