Clinical Aspects of Aging Flashcards
4 major features of aging?
- destructive
- progressive
- partly determined by genetic code
- universal (mammalian species)
-progressive, universal physiological aging changes
normal/healthy aging
includes disease commonly occurring in aging such as HTN, CAD, T2DM
usual (chronically ill, frail)
preserved function and compression of morbiditiy
successful aging
increased vulnerability and increased risk of impaired function refer to increasing?
frailty
reduced physiologic reserve to maintain homeostasis during periods of stress, physiologic demands associated with exertion and acute illness
homeostenosis
changes in vision in elderly?
decreased visual acuity, lateral motion, depth perception, contrast sensitivity; increased glare sensitivity
implications of vision changes?
quality of life, night driving, fall risk, medication issues (reading, finding white pill in white box)
- loss of high frequencies first
- bilateral, symmetrical, slowly progressive
presbycusis
- dysequilibrium of aging
- vestibular degeneration
- diagnosis of exclusion
presbystasis
increased theshold to tast salt and sweet, gives perception that food is poorly _______, increased salt may have potential negative impact on HF and HTN
seasoned
physiologic anorexia of aging:
- reduced ______ of gastric fundus, early antral filling
- decreased gastric _______
- increased circulating CCK
- decrease in dynorphins - eating drive
stretch/relaxation
emptying
- age related disease of contractile amplitude
- after 80, effective esophageal contractions may not occur after a swallow
- increased microaspiration risk
presbyesophagus
gastric:
- ______ HCl and gastric emptying
- disruption of gastric mucosal _______, increased risk of PUD
decreased
barrier
- reduced absorption of iron, zinc, B12, folic acid, lactose
- reduced vitamin D receptors in gut leads to impaired absorption of _______
- bacterial overgrowth due to long term use of _______
calcium
PPIs