Clinical Application to High Blood Pressure Flashcards

1
Q

Diagnosis of HTN

A

> 140 and/or 90
On 2 or more office visits
and/or
Current use of antihypertensive medications

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2
Q

Prevelance Demographics

A

AA>Caucasians> Mexican-Americans

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3
Q

Prehypertension

A

Systolic: 120-139
Diastolic 80-89
Lifestyle modifications, no meds

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4
Q

Hypertension

A
Stress
Weight
Blood glucose
Smoking
Caffeine
Cardiopulmonary fitness
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5
Q

Malignant Hypertension

A
Hypertastic arteriolosclerosis
Younger male AA
BP >200/120
Signs/Symptoms: headache, nausea, vomiting, encephalopathy, papilledema, retinal hemorrhage
Renal failure
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6
Q

Psuedohypertension

A

Peripher arteries are rigid from advanced arteriosclerosis, cuff cannot compress the artery
Diabetes mellitus
Chronic renal failure
PAD

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7
Q

Isolated Systolic Hypertension

A

With age systolic BP rises while diastolic falls
Widened pulse pressure
Systolic > 140
Diastolic

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8
Q

Resistant Hypertension

A

Failure to reach targeted BP in patients who are on drug therapies (3 drugs including diuretic)
Look into secondary causes

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9
Q

Hypertensive Urgency

A

Severe elevation without acute end-organ damage
> 180/120 with headache
Can be sent home from office with F/U (if pressure is responsive to meds)
Most commonly are patients who stopped taking their meds

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10
Q

Hypertensive Emergency

A

Severe elevation WITH acute end-organ damage
Hypertensive encephalopathy, intracerebral hemorrhage, acute MI, acute LV failure, acute aortic dissection, renal crisis, acute glomerulonephritis, microangiopathic hemolytic anemia
Requires hospitalization to lower BP (IV meds, given in ICU)

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11
Q

Hypertensive Emergency Management

A

Reduce MAP 10-20% per hr
Reduce up to 25-30% in first 24 hours
Transition to oral meds after target pressure stabolizes
EXCEPTIONS: Dissection aortic aneurysm (rapidly lower pressure), acute phase of ischemic stroke (reperfusion candidates, need to rapidly lower pressure to be eligible for tPA)

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12
Q

HTN Clinical Manifestations

A

Usually none
Silent killer
No symptoms until end organ damage

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13
Q

Diagnosis

A
ECG
Urinalysis
Blood glucose and hematocrit
Serum K, creatinine, estimated GFR, Ca
Fasting lipid profile
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14
Q

Complications of HTN

A

Risk of CVD beginning at 115/75 and doubles with each increment of 20/10 up to 185/115

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15
Q

Benefits of Lowering Blood Pressure

A

For each 20 mmHg decrease in systolic BP: 30% decrease heart and 40% decrease risk of stroke mortality

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16
Q

Treatment Goals i/r Age

A

Age 60 150/90

17
Q

Antihypertensive Agents

Thiazide Diuretic

A

Hydrocholorithiazide

Chlorthalidone

18
Q

Antihypertensive Agents

ACE Inhibitors

A

Lisinopril,
Enalapril
Captopril
Benazepril

19
Q

Antihypertensive Agents

ARB

A

Losartan

Valsartan

20
Q

Antihypertensive Agents

Beta Blockers

A
Metoprolol
Atenolol
Carvedilol
Labetalol
Esmolol
21
Q

Antihypertensive Agents

Calcium Channel Blockers

A

Diltiazem
Verapamil
Amlodipine
Nifedipine

22
Q

Tx Of Resistant Hypertension

A
Look at potential causes
Improper BP measurement
Excess Na intake
Inadequate diuretic therapy
Medication (inadequate doses)
Drug actions/interactions (NSAIDs, illicit drugs, sympathomimetics, oral contraceptives)
OTC drugs/herbal supplements
Excess alcohol intake