Clinical: Antidepressants (Ud) Flashcards

1
Q

When were SSRI’s created?

A

The 80s

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2
Q

Give an example of an SSRI.

A

Fluoxetine one of the most commonly prescribed antidepressants in the UK.

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3
Q

What do SSRI’s do?

A

Block serotonin reuptake so it starts in the synapse for longer.
=a prolonged antidepressant effects of serotonin being repeatedly binded with receptors on the post synaptic neutron.

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4
Q

Evaluate the supporting evidence of drug treatments for unipolar depression.

A

Cipriani et al:
Conducted a meta-analysis of 21 studies of antidepressants. All drugs were found to be more effective than the placebo.

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5
Q

What is the opposing evidence of drug treatments for unipolar depression?

A

Cipriani:
Also found varying effectiveness of anti-depressants. Eg: the most effective drug had the lowest compliance rate meaning people were likely to stop taking them.

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6
Q

What is a different theory to drug treatments for unipolar depression?

A

Drug tests symptom not cause:
Drugs stabilise the brain but only while the patient is on medication. CBT can teach coping mechanisms that help an individual identify and tackle the root cause.

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7
Q

What is the application of drug treatments for unipolar depression?

A

Side effects:
If we know the side effects that antidepressants can cause then we can manage them by monitoring diet and medication.
Increases credibility as more people are likely to accept it.

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