Clinical 4 - Pulmonary Diseases of Vascular Origin Flashcards
What is the most common originating spot for a pulmonary embolism?
DVT of lower extremities
What is commonly used to diagnose DVT?
Duplex ultrasonography
What are the clinical findings of PE?
Tachypnea, dyspnea, syncope, acute hypertension, wheezing, friction rubs
What is the gold standard for diagnosing PE?
Spiral CT
What 3 drugs can treat PE/DVT?
LMWH
UFH
Warfarin
What agents are used to treat massive cases of PE?
Thrombolytic agents
What are the diagnostic features of Wegeners granulomatosis?
Necrotizing granulmatous vasculitis
Glomerulonephritis
Name two important signs of Wegeners?
Nasal septal perforation
Ulceration of the vomer bone
What is the lab result diagnostic for Wegeners?
C-anca
How do you treat Wegeners?
Corticosteroids and cyclophosphamide
What are the diagnostic features of Churg-Strauss syndrome?
Increased levels of IgE and eosinophils
Refractory asthma
What are the clinical findings in Behcet disease?
Apthous orogenital ulcerations
Uveitis
Cutaneous nodules
Synovitis
What arteries are most common in Takayasu arteritis?
Aorta and major branches
Pulmonary artery is involved
What are the clinical presentations of mixed cryoglobulinemia?
Episodes of purpura
Arthralgia
Weakness
Multiorgan involvement
What are the complications of mixed cryoglobulinemia?
Glomerulonephritis and pulmonary insufficiency
What hypersensitivity reaction is involved in Goodpastures syndrome?
Type II
What are the immunological findings of Goodpastures?
Anti-GBM antibody
Diffuse alveolar damage
What are the classic features of Goodpastures?
Recurrent hemoptysis
Pulmonary insufficiency
Renal failure
Cresentric glomerulonephritis
What arterial pressure is needed to diagnose pulmonary arterial hypertension?
Arterial pressure greater than 25 mmHg
What are the symptoms of pulmonary arterial hypertension?
Increased RV systolic pressure
Right sided heart failure
