clin path 2 Flashcards
anemia
a reduction in the RBC, HGB and PCV
clinical signs of anemia
pale mucous membranes, weakness, exercise intolerance, lethargy, tachypnea, tachycardia, syncope
general causes of anemia
blood loss (hemorrhages)
hemolysis
decreased production of RBCs
regenerative causes of anemia
blook loss (hemorrhages)
hemolysis
non-regenerative causes
decreased production
blood loss (hemorrhage)
blood vessel damage
tramua, ulcers, neoplasia, inflammation
hemolysis
intra and/or extravascular RBC destruction
Decreased production
chronic renal failure
anemia of chronic disease
severity of anemia guidlines
mild-dog>33% cat>26%
moderate-dog>24% cat>23%
marked-dog<23% cat<23%
acute blood loss
external hemorrhage or internal hemorrhage
patient loses all blood components in equal portions
acute blood loss CBC findings
severity of anemia-mild to marked
decreased total protein
reticulocytosis (within 2-3 days)
increased BUN
Chronic blood loss
internal blood loss into a body cavity
external blood loss
patient RBC are able to adapt
chronic blood loss CBC
mild to marked
decrease total protein
reticulocytosis (unless iron deficiency has resulted in decreased erythropoiesis)
chronic CBC finding for iron deficiency
increased MCV (microcytic) and decreased MCHC (hypochromic)
hemolysis vs anemia
hemolysis-RBC destruction
anemia-when destruction exceeds production