Clin Path 1

Question 1

Erythrocytes

Answer 1

Red blood cells

Question 2

Erythrocyte production

Answer 2

produced within the bone marrow

Question 3

Erythrocyte function

Answer 3

synthesize hemoglobin and transport oxygen (via bound to hemoglobin

Question 4

PCV

Answer 4

Packed cell volume
percentage of RBC within a whole blood sample
measured with a microhematocrit tube and centrifuge

Question 5

HCT

Answer 5

hematocrit
% of blood volume filled by RBC
determined from a hematology analyzer
percentage calculated
calculated by RBC and mean corpuscular volume (MVC)

Question 6

RBC

Answer 6

Red blood cell count
number of RBCs/per unit of blood

Question 7

HGB

Answer 7

grams of hemoglobin/100ml of blood
hemoglobin concentration
determined by an hematology analyzer

Question 8

Erythropoiesis

Answer 8

production of RBC

Question 9

erythroid hyperplasia

Answer 9

appropriate bone marrow response to peripheral need for RBC
ex. blood loss resulting in a decrease in peripheral tissue oxygen tension

Question 10

erythroid hypoplasia

Answer 10

bone marrow is not responding to peripheral need for RBC
due to a variety of causes

Question 11

Reticulocyte

Answer 11

stage just before a mature RBC
cells lack a nucleus but still contain organelles and RNA
released from the ,arrow in response to peripheral need for RBC
NOT in horses
reticulocytosis indicates regenerative anemia

Question 12

Reticulocyte %

Answer 12

percentage of RBC that are reticulocytes

Question 13

RBC indices

Answer 13

mean corpuscular volume (MCV)
mean corpuscular hemoglobin concentration (MCHC)
MCH

Question 14

MCV

Answer 14

mean corpuscular volume or average volume of circulating RBC
provides a volume of average RBC
larger cells=higher MCV
smaller cells=lower MCV

Question 15

MCHC

Answer 15

mean corpuscular hemoglobin concentration or average concentration og hemoglobin within circulating RBC
cells with less hemoglobin=lower MCHC
cells can not have excess hemoglobin

Question 16

Anemia characterized

Answer 16

first by severity
then by regenerative or non-regenerative

Question 17

increased number in blood

Answer 17

regeneration and is an appropriate response to anemia

Question 18

normal PCV

Answer 18

dog:45
Cat:35
Cow:35

Question 19

RBC indices microcytic

Answer 19

iron deficiency-support low MCHC
portosystemic shunt-unknown mechanism and support high ammonia

Question 20

RBC indices Macroytic

Answer 20

erythriod regeneration-support: reticulocytosis and low MCHC
RBC agglutination (artifactually high MCV)

Question 21

Hypochromic

Answer 21

iron deficiency
support low MCV
erythroid regeneration
support increased reticulocytes

Question 22

Hypochromic

Answer 22

iron deficiency
support low MCV
erythroid regeneration
support increased reticulocytes

Question 23

hyperchromic

Answer 23

not real
result of artifact (in vitro or in vivo)
intravascular hemolysis
numerous heinz bodies
lipemia

Question 24

macrocytic, hypochromic

Answer 24

look for a reticulocytosis to support erythroid regeneration

Question 25

microcytic, hypochromic

Answer 25

most compatible with iron deficiency (albeit late stage; early iron deficiency is hard to identify as indices are normal
can be regenerative or non-regnerative

Question 26

Metarubricytosis

Answer 26

presence of nRBCs in peripheral blood

Question 27

increased nRBC

Answer 27

do not equal regeneration
increased nRBCs may accompany regeneration

Question 28

appropriate metarubricytosis

Answer 28

occurs concurrently with a regenerative anemia