Clin Med: Cor Pulmonale and Pulm HTN Flashcards
Cor Pulmonale Pathophysiology
Right sided heart failure due to chronic pulmonary disease
results in increased right sided end diastolic pressure and right atrial enlargement
Acute Cor Pulmonale is usually due to
PE
Chronic Cor Pulmonale is usually due to
COPD
What are two things that are not considered Cor Pulmonale
congenital heart disease and right sided HF due to left sided HF
Effects of Cor Pulmonale
peripheral edema due to elevated R atrial pressure
ascites
increased RBCs to optimize oxygenation (Plethora)
Drowsiness and CO2 retention
What is the core cause of Cor Pulmonale
Pulmonary HTN
Pulm HTN pathophysiology
increased pulmonary artery pressure due to intimal fibrosis (smooth muscle hypertrophy) –> Cor pulmonale
Two types of Pulm HTN
primary - rare (idiopathic and self perpetuating)
secondary - more common (due to lung or blood vessel disease)
Common cause of Pulm HTN
OSA
Sx of Pulm HTN
SOB with exertion
Syncope with exertion (severe cases)
Sometimes: CP, Cough, fatigue
Late finding of Pulm HTN
tricuspid regurgitation
Evaluation of Pulm HTN
X-ray
CT scan
ECHO
Cath Lab - to find R sided pressure
most common treatment of Pulmonary HTN
Phosphodiesterase inhibitors - sildenafil