Class Ten Flashcards
skeletal muscle is..
voluntary muscle
skeletal and cardiac muscle are..
striated muscle
three different types of muscle
skeletal
cardiac
smooth
what do tendons attach
muscle to bone
abducting vs adducting
abducting - moving away from body
adducting - moving towards the body
antagonistic muscles
muscles that are responsible for movement in opposite directions
synergistic muscles
muscles that move a joint in the same direction
single skeletal muscle cell
individual muscle fibers
cell membrane of a myofiber
sarcolemma
what do myofibrils do
generates contractile force of skeletal muscle
make up the myofibers
proteins in myofibril that generates contraction
actin and myosin
actin forms..
thin filaments
myosin forms..
thick filaments
what makes up myofibrils
sacromeres
what are sacromeres bound by
two Z lines
regions of a sarcomere only composed of thin filaments
I bands
full length of the thick filament is..
the A band
region composed of only thick filaments
H zone
what causes contraction
thin and thick filaments sliding across each other + bringing the Z lines closer together
what powers filament sliding
ATP hydrolysis
describe the process of the contractile cycle
myosin head binds to myosin binding site on actin (cross bridge formation)
myosin head pulls on actin chain (power stroke, ADP is released)
actin is released by the myosin head by binding of a new ATP molecule
what needs to be present for contraction to occur
calcium
troponin-tropomyosin complex
prevents contraction when calcium is not present
what is tropomyosin
protein that blocks myosin binding sites (head can’t bind)
what is troponin
protein that is bound to tropomyosin that can bind calcium
what happens when troponin binds to calcium
troponin changes shape which moves tropomyosin out of the way so the myosin head can bind
what is a neuromuscular junction
synapses between an axon terminus and a myofiber
what neurotransmitter is used at the NMJ
ACh
purpose of t tubules
deep invaginations of the cell membrane → allows AP to travel into the thick cell
purpose of the sarcoplasmic reticulum
stores calcium ions and releases them into the sarcoplasm on the generation of action potential during muscle contraction
what is rigor mortis
rigidity of skeletal muscles which occurs after death → complete ATP exhaustion
what causes cramps
temporary lack of ATP
slow vs fast twitch fibers
depends on their contractile speeds
type 1 slow twitch fibers
aka red slow twitch → high myoglobin content
have good oxygen content & can maintain contraction for a long time
e.g. useful for marathons
type IIA fast twitch fibers
contract quickly and somewhat resistant to fatigue
have more mitochondria than type IIB
type IIB fast twitch fibers
aka white fast twitch fibers → lack of mitochondria
contract quickly with great force
fatigue very, very quickly
functions of the skeletal system
support the body
framework for movement
protect vital organs
store calcium
synthesize formed elements of blood
hematopoiesis
creation of formed elements in the blood
occurs in the marrow of the flat bones
axial skeleton
skull, vertebral column and rib cage
connective tissue cells are derived from..
the fibroblast
what cells are derived from fibroblasts (3)
adipocytes, chondrocytes & osteocytes
dense vs loose connective tissue
dense - tissues that have a lot of fibers (e.g. collagen)
loose - packing tissue and fat tissue
two bone shapes
flat and long
location of hematopoiesis
flat bones
main shaft of a long bone
diaphysis
flared end of a long bone
epiphysis
diaphysis of a long bone is composed of..
compact bone
bone can either be..
compact or spongy