Class 1 E1 Flashcards

1
Q

R-O-H

A

hydroxyl

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2
Q

hydroxyl groups

A

participate in rxns including esterification, dehydration, oxidation.

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3
Q

R-C-H
||
O

A

carbonyl (aldehydes and ketones)

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4
Q

carbonyl group

A

polar, subjected to nucleophilic attack by hydroxy / amino groups.

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5
Q

R-C-O
||
O

A

carboxyl

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6
Q

carboxyl

A

weak acids, form esters and amides.

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7
Q

R1-C-O-R2
||
O

A

ester

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8
Q

ester

A

result of hydroxy and carboxylic acid rxns, commonly found in lipids.

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9
Q

R-S-H

A

thiol

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10
Q

thiol

A

hydroxyl analogs, found in cysteine.

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11
Q

R-S-S-R’

A

disulfide

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12
Q

disulfide

A

result of rxn of two thiol groups, reducing agents cleave disulfide, restoring two thiols.

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13
Q

R1-C-S-R2
||
O

A

thioester

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14
Q

thioester

A

large negative free E of hydrolysis

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15
Q

R-NH3

A

amino

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16
Q

amino

A

lone pair can acquire a proton, leads to positively charged amino group.

17
Q

R-(C=O)-(N-R)-H

A

amide

18
Q

amide

A

formed via amine and carboxylic acid rxn; peptides are amide linkages found in proteins.

19
Q

phosphates

A

inorganic phosphate Pi

20
Q

phosohoesters

A

phosphate group plus hydroxyl group

21
Q

phosphoanhydrides

A

found in nucleoside triphosphates like ATP, large negative free E of hydrolysis