CLASP-Sepsis Flashcards
What percentage of drugs are killed by minimum inhibitory concentration of a drug?
99.9%
Where are septic emboli in the brain likely to migrate from?
left sided endocarditis
Which organisms are most likely to cause a diverticular abscess?
coliforms and anaerobes
What is alpha haemolysis?
partial haemolysis
What organisms typically cause endocarditis?
Staph aureus, viridans, HACEK group and escherichia species
What are the components of the qSOFA scoring?
Altered mental state
RR >22
SBP <100
Which immunoglobulin is released first in infection’?
IgM- it has a weak affinity and is poorly specific. IgG is produced later
What is a complication of E.coli 0157?
Haemloytic uraemic syndrome
What is a complication of strep throat?
Rheumatic fever
What is the best test for c.diff infection?
Stool toxin test
Which antibiotic is active against gram positive organisms only?
Vancomycin
How many blood cultures should be taken from a patient with suspected sepsis due to endocarditis before antibiotics are given?
3 blood cultures taken over an hour then antibiotics
What are the 4 C’s that cause a C.diff infection?
Clindamycin, ciproflaxacin, co-amoxiclav, ceftazidimine
Is haemophilus influenzae gram negative or positive?
It is a gram negative coccobacillus
What is the treatment of haemophilus influenzae?
Amoxicillin or doxycyline
Which cells does HIV infect?
CD4 T helper cells
What is the expected urine output?
0.5mls/kg/hr
Where would septic emboli in the lungs migrate from?
Right sided endocarditis
What is streptococcus?
Gram positive chains
What is the recommenced fluid intake for a septic patient?
30ml/Kg
Which criteria is used to assess endocarditis?
Dukes criteria
Which veins are you likely to insert a central line into in PWID?
Femoral vein and internal jugular vein
Which antibiotic is active against gram negative organisms only?
Gentamicin
How would you treat MRSA in the bloodstream?
IV vancomycin
a NEWS score of what suggests sepsis?
> 5
Which antibiotics are beta lactams?
Carbepenems, penicillin, cephalosporins
What is included in the SIRS criteria?
HR >90
RR >20
Temp >38
WBC >1200
Mycoplasma pneumoniae is a common organism in which age group?
Children and young adults
Which antibiotic covers anterococci?
Amoxicillin
