CLASP-Sepsis

Question 1

What percentage of drugs are killed by minimum inhibitory concentration of a drug?

Answer 1

99.9%

Question 2

Where are septic emboli in the brain likely to migrate from?

Answer 2

left sided endocarditis

Question 3

Which organisms are most likely to cause a diverticular abscess?

Answer 3

coliforms and anaerobes

Question 4

What is alpha haemolysis?

Answer 4

partial haemolysis

Question 5

What organisms typically cause endocarditis?

Answer 5

Staph aureus, viridans, HACEK group and escherichia species

Question 6

What are the components of the qSOFA scoring?

Answer 6

Altered mental state
RR >22
SBP <100

Question 7

Which immunoglobulin is released first in infection’?

Answer 7

IgM- it has a weak affinity and is poorly specific. IgG is produced later

Question 8

What is a complication of E.coli 0157?

Answer 8

Haemloytic uraemic syndrome

Question 9

What is a complication of strep throat?

Answer 9

Rheumatic fever

Question 10

What is the best test for c.diff infection?

Answer 10

Stool toxin test

Question 11

Which antibiotic is active against gram positive organisms only?

Answer 11

Vancomycin

Question 12

How many blood cultures should be taken from a patient with suspected sepsis due to endocarditis before antibiotics are given?

Answer 12

3 blood cultures taken over an hour then antibiotics

Question 13

What are the 4 C’s that cause a C.diff infection?

Answer 13

Clindamycin, ciproflaxacin, co-amoxiclav, ceftazidimine

Question 14

Is haemophilus influenzae gram negative or positive?

Answer 14

It is a gram negative coccobacillus

Question 15

What is the treatment of haemophilus influenzae?

Answer 15

Amoxicillin or doxycyline

Question 16

Which cells does HIV infect?

Answer 16

CD4 T helper cells

Question 17

What is the expected urine output?

Answer 17

0.5mls/kg/hr

Question 18

Where would septic emboli in the lungs migrate from?

Answer 18

Right sided endocarditis

Question 19

What is streptococcus?

Answer 19

Gram positive chains

Question 20

What is the recommenced fluid intake for a septic patient?

Answer 20

30ml/Kg

Question 21

Which criteria is used to assess endocarditis?

Answer 21

Dukes criteria

Question 22

Which veins are you likely to insert a central line into in PWID?

Answer 22

Femoral vein and internal jugular vein

Question 23

Which antibiotic is active against gram negative organisms only?

Answer 23

Gentamicin

Question 24

How would you treat MRSA in the bloodstream?

Answer 24

IV vancomycin

Question 25

a NEWS score of what suggests sepsis?

Answer 25

> 5

Question 26

Which antibiotics are beta lactams?

Answer 26

Carbepenems, penicillin, cephalosporins

Question 27

What is included in the SIRS criteria?

Answer 27

HR >90
RR >20
Temp >38
WBC >1200

Question 28

Mycoplasma pneumoniae is a common organism in which age group?

Answer 28

Children and young adults

Question 29

Which antibiotic covers anterococci?

Answer 29

Amoxicillin