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Biochemistry > Citric Acid Cycle<3 > Flashcards

Citric Acid Cycle<3 Flashcards

1
Q

what do most fuels enter the CAC as?

A

Acetyle coenzyme A

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2
Q

CAC is the final common pathway for what?

A

oxidation of fuel molecules e.g., fatty acids and amino acids

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3
Q

where does the CAC take place?

A

mitrocondria

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4
Q

what is the completion of the CAC?

A

completion from glucose in the cytoplasm to end products of metabolism -> E generation, CO2 and water

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5
Q

what does the CAC start with?

A

complete oxidation of glucose derivatives

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6
Q

the most ATP is generated from what?

A

aerobic processing of glucose

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7
Q

what does the CAC harvest

A

high energy electrons

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8
Q

what are fuel molecules?

A

C-compounds capable of being oxidised

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9
Q

pyruvate generated from glucose is ——— ———- to form ———

A

OXIDATIVLEY DECARBOYLATED to form ACETYLE COA

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10
Q

what is the CAC

A

gateway to aerobic metabolism

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11
Q

what is the purpose of the CAC

A

to harvest high energy electrons from carbon fuels

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12
Q

the electrons removed from acetylCoA are used to form what?

A

NADH and FADH2 (electron carriers)

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13
Q

what are NADH and FADH2

A

electron carriers

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14
Q

how many molecules of ATP are yielded when the e- carriers are oxidised by oxygen in oxidative phosphorylation

A

9

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15
Q

when are these electrons released?

A

in the deoxidation of NAHD and FADH2.

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16
Q

once the e-have been released what do they do?

A

flow through a series of membrane proteins (e- transport chain)

17
Q

to transform pyruvate to AcetyleCoA it require what?

A

3 enzymes of pyruvate dehydrogenase and 5 coenzymes i.e. FAD

18
Q

when acetylecoa is oxidised into CO2 what does it generate? and what can these do?

A

high energy e-

they can power synthesis of ATP

19
Q

what can the defects in the CAC contribute to?

A

cancer

20
Q

net reaction of CAC?

A

acetylecoA + 3NAD+ +FAD + ADP + Pi + CoA–>

2CO2+ 3NADH + FADH2 + ATP +2H+ +CoA

21
Q

disruption of pyruvate metabolism can be the cause of?

A

beriberi poisoning (an arsnic poisoning)

Biochemistry (12 decks)

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