Citomegalovirus Congénito Flashcards

1
Q

Periodo de mayor transmisión de CMV congénito

A

TERCER TRIMESTRE

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2
Q

Clínica CMV congénito

A

90% asintomáticos
5-17% pérdida auditiva neurosensorial, coriorretinitis, déficit neurológico desde primero 2 días de vida

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3
Q

Hallazgos CMV congénito más frecuentes

A

RMN anormal
TAC anormal
US craneal anormal
TRANSAMINASEMIA
TROMBOCITOPENIA
HSM

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4
Q

Factores de riesgo para embarazada

A

Exposición frecuente y prolongada a niños pequeños
Menores de dos años Excretan virus en orina y saliva 24 meses

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5
Q

Manifestación primo infección mujer embarazada con CMV

A

Asintomática
30% fiebre, cuadro gripal, mononucleósido
PFH, linfocitosis, trombocitopenia

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6
Q

Dx CMV congénito

A

Aislamiento viral en cultivo de tejidos obtenidos de biopsia o saliva u orina en primeros 15 días de vida

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7
Q

Tx CMV congénito

A

GANCICLOVIR
VALGANCICLOVIR

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8
Q

Efecto adverso ganciclovir y valganciclovir

A

Neutropenia

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9
Q

Primera causa de hipoacusia y sordera neurosensorial

A

CMV

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