Circulatory system Flashcards
Blood functions
- Transport of gases, nutrients, and waste products
- Transport of molecules
- Transport of regulatory molecules
- regulation of pH, osmosis, and body temperature
- Protection
- Clot formation
Plasma
liquid matrix that contrains blood cells and other things being transported
formed elements
cells in the blood stream
Plasma elements
proteins, ions, nutrients, waste products, gases, hormones, and water
Formed elements elements
platelets, white blood cells, red blood cells
Plasma proteins
albumin, globulins, and fibrinogen
Albumin
prevents fluid from leaking out of blood vessels
globulins
part of the immune system and transport molecules
Fibrinogen
a clotting factor
Serum
plasma without clotting factors
Serum
plasma without clotting factors
Hematopoiesis
the process that produces formed elements
Red blood cell making
- Hematopoietic stem cell
- Myeloid stem cell
- Proerythroblast
- Early erythroblast
- Intermediate erythroblast
- late erythroblast
- Reticulocyte
- Red blood cell
Red blood cells
the most abundant substance in the formed elements that transports oxygen and carbon dioxide
Red blood cells shape
biconcave disk that increases surface area for more gas exchange they can also decrease in size to more easily pass through capillaries
Capillaries
where red blood cells exchange gases
Hemoglobin
a red protein that binds to oxygen and co2 for transport in red blood cells
Oxygen transport
- O2 enters red blood cell
2.
Hemoglobin structure
Four protein chains called globin are each bound to one heme group. Each heme contains one iron atom which attaches to O2.
Red blood cell colour
When hemoglobin is bound to O2 it is bright red. When it does not have oxygen it is a dark red.
Carbonic anhydrase
an enzyme found in red blood cells that catalyzes the reaction between carbon dioxide and water to create bicarbonate and then the bicarbonate can be transported by the blood
ways of transporting co2
Turing it into bicarbonate, binding it to protiens and dissoliving in plasma
Proerythroblasts
the stem cell that creates red blood cells
When does red blood cells lose their nucleus
during the late erythroblast stage
What signals the creation of red blood cells
low blood O2 levels due to decreased number of red blood cells, lung issues, hemoglobin issues, and issues in blood transport
erythropoietin
a glycoprotein that stimulates red bone marrow to produce more red blood cells
how are red blood cells disposed?
macrophage breaks down hemoglobin > globin is broken into amino acids > iron is released from heme group > heme molecules are converted to bilirubin > bilirubin is excreted
pulmonary circulation
systems of blood vessels that carry blood from the right ventrile to the lungs and back to the left atrium
systemic circulation
blood vessels that carry blood from the left ventrile to the body and back to the right atrium
heart functions
generating blood pressure, routing blood, ensuring one way flow, and regulating blood supply
apex
point of the heart
base
flat end of the heart