Circoviridae

Question 1

Circoviridae
\_\_\_\_\_ stranded , \_\_\_\_\_ DNA/RNA genome
-ambisense or \_\_\_\_ sense
-limited ORFs and gene products
Envelope?
Morphology?
Size?
-Durable in environment

Answer 1

Circoviridae
SINGLE stranded , CIRCULAR DNA genome
-ambisense or POSITIVE sense
-limited ORFs and gene products
Envelope? NO
Morphology? ICOSAHEDRON
Size? 17-22 nM
-Durable in environment

Question 2

Chicken Anemia Virus (CAV)
Dz: CAV dz, hemorrhagic syndrome, \_\_\_\_-wing dz, anemia dermatitis syndrome
Host: 
Transmission: \_\_\_\_\_, \_\_\_\_\_, \_\_\_\_\_
-Horizontal: \_\_\_\_\_\_ or \_\_\_\_\_ contact
-Vertical: \_\_\_\_\_\_ to \_\_\_\_\_
Incubation: _ to _ wks
Immunity: Maternal Abs protective against DZ (not infection) until approx _ \_\_\_\_ of age

Answer 2

Chicken Anemia Virus (CAV)
Dz: CAV dz, hemorrhagic syndrome, BLUE-wing dz, anemia dermatitis syndrome
Host: 
Transmission: ORONASAL, FECAL, URINARY
-Horizontal: INGESTION or DIRECT contact
-Vertical: INFECTED HEN to EGGS
Incubation: 1 to 2 wks
Immunity: Maternal Abs protective against DZ (not infection) until approx 3 WEEKS of age

Question 3

Clinical presentation, guess that dz:

• Chick 1-2 weeks old
• anorexia, lethargy, depression, decreased hematopoiesis
• hemorrhages in subQ and mm.
• immunosuppression: atrophy of lymphoid organs/tissue, bone marrow, thymus, bursa, spleen

Answer 3

Chicken Anemia

Question 4

Psittacine Beak and Feather Dz viruses
_ genotypes
Host range: cockatoos, parrots, budgerigars
Transmission: Shed in ____ follicular epithelium, ____
Age: ______ and ____ birds
Clinical Pres:
-Dystrophic _____ (necrosis, annular constrictions, shaft hemorrhage, loss)
-_____ dystrophy, reduced growth
-abnormal plumage or color
-immunosuppression

Answer 4

Psittacine Beak and Feather Dz viruses
9 genotypes
Host range: cockatoos, parrots, budgerigars
Transmission: Shed in FEATHER follicular epithelium, FECES
Age: FLEDGLINGS and YOUNG birds
Clinical Pres:
-Dystrophic FEATHERS (necrosis, annular constrictions, shaft hemorrhage, loss)
-BEAK dystrophy, reduced growth
-abnormal plumage or color
-immunosuppression

Question 5

Are there vaccines available for avian circoviruses?

Answer 5

Fuck no

Question 6

Porcine Circovirus-1 (pathogenicity unknown) and Porcine circovirus-2
Dz: _____(PMWS), ___-2 _______ pneumonia (PRDC), ______ (PDNS), enteritis, reproductive failure
Host:
Transmission: PCV2 infections common, seroconversion occurs after colostral abs decline at the end of the nursery period
Shedding: _____, _____, _____, present in blood, shed in _____ for 45 days

Answer 6

Porcine Circovirus-1 (pathogenicity unknown) and Porcine circovirus-2
Dz: POST WEANING MULTI SYSTEMIC WASTING SYNDROME (PMWS), PCV-2 ASSOCIATED pneumonia (PRDC), PORCINE DERMATITIS AND NEPHROPATHY SYNDROME (PDNS), enteritis, reproductive failure
Host: DOMESTIC SWINE
Transmission: PCV2 infections common, seroconversion occurs after colostral abs decline at the end of the nursery period
Shedding: FECES, URINE, MUCUS, present in blood, shed in SEMEN for 45 days