Circle of Willis - Lecture 3 Flashcards

1
Q

what forms the circle of willis

A

anterior communicating

internal carotid

posterior communicating

posterior cerebral

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2
Q

left and right sides are

A

mirror images of each other

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3
Q

what happens if one of the vessels is occluded or temporarily clipped

A

may be distal collateral flow via the communicating arteries

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4
Q

anastomoses

A

interconnections b/w blood vessels

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5
Q

what do anastomoses do

A

overlapping blood supply

safety mechanism

retrograde filling

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6
Q

examples of anastomoses

A

circle of willis

ophthalmic artery and external carotid

surface branches of anterior, middle, posterior

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7
Q

blood flow to CNS is

A

controlled

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8
Q

how is blood flow in CNS controlled

A

autoregulation

metabolite control

autonomic nervous system control

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9
Q

autoregulation

A

cerebral vessels themselves act to maintain constant flow

smooth muscles of arteries and arterioles are stretch

–> sensitive and respond to the changes in blood pressure

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10
Q

stroke

A

CVA

cerebrovascular accident

failure of safety mechanisms

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11
Q

stroke stats

A

3 cause of death for US adults

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12
Q

transient ischemic attack

A

TIA

recovery is complete w/in 24 hours

10% of patients will go on to have a stroke

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13
Q

TIA is

A

warning sign

very significant warning sign of a stroke

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14
Q

definition of stroke

A

rapidly developed clinical sign of focal disturbance of cerebral fxn of presumed vascular origin and more than 24 hours

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15
Q

sub-types of strokes

A

ischemic

hemorrhage

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16
Q

ischemic

A

obstruction to one of major cerebral arteries

brainstem strokes are less common

more common type of stroke

clot

17
Q

hemorrhage

A

bleed

9% are caused by hemorrhage to the deep parts of the brain

pt are usually hypertensive

longer/harder recovery

18
Q

cerebral vasculature

A

arteries

capillaries

veins

19
Q

arteries

A

thicker walls

lack of external elastics

astrocyte processes are parts of the walls –> BBB

surrounded by arachnoid/pia membranes

20
Q

capillaries

A

surround by astrocyte processes

21
Q

veins

A

thinner walls

no valves/muscles
–>allow flow in either direction
–>reversal on flow in occlusion