Brain During Development Flashcards

1
Q

what are the last portions of the neural tube to close called

A

anterior and posterior neuropores

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2
Q

when do the last portions of the neural tube close

A

end of the embryonic week

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3
Q

what does the neural tube surround

A

fluid filled central cavity

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4
Q

rostral end of the neural tube

A

larger and more irregular

gives rise to the brain

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5
Q

closure of caudal neruopore

A

corresponds to the upper lumbar segments of the cord

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6
Q

how does the brain develop

A

3 major brain divisions –> occur @ 3/4 week

secondary divisions –> @ 5th week

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7
Q

3 major brain divisions during development

A

prosencephalon (forebrain)

mesencephalon (midbrain)

rhombencephalon (hindbrain)

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8
Q

secondary divisions –> prosencephalon

A

telencephalon

diencephalon

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9
Q

secondary divisions –> rhombencephalon

A

metencephalon

myelencephalon

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10
Q

rhombencephalon –> myelencephalon –> mature brain?

A

medulla oblangata

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11
Q

rhombencephalon –> metencephalon –> mature brain?

A

pons and cerebellum

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12
Q

mesencephalon –> mature brain?

A

midbrain

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13
Q

prosencephalon –> diencephalon –> mature brain?

A

thalamus

epithalamus

hypothalamus

subthalamus

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14
Q

prosencephalon –> telencephalon–> mature brain?

A

cerebral hemispheres

corpus striatum

cerebral cortex

white matter

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15
Q

slide 60

A

pic

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16
Q

what do flexures do

A

accommodate the shape changes of the brain as it becomes round

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17
Q

different flexures

A

cervical

mesencephalic

pontine

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18
Q

cervical flexure

A

jxn of the rhombencephalon w/ the spinal cord

19
Q

mesencephalic flexure

A

level of the midbrain

20
Q

pontine flexure

A

in the metencephalon

21
Q

when do meninges first appear

A

4th week as single mesodermally derived primary meninx

22
Q

when do fluid-filled spaces appear

A

w/in the primary meninx

1 week later

giving rise to meninges

23
Q

layers of the meninges from inside out

A

pia mater –> arachnoid –> dura mater

24
Q

pia mater

A

closest to nervous tissue

25
Q

arachnoid

A

interposed b/w the pia and dura mater

spiderweb-like

26
Q

dura mater

A

lines the cranial cavity and the spinal canal

27
Q

what will permeate the CSF

A

ventricle lateral

28
Q

how does the ventricle lateral develop

A

neural tube will undergo changes and finally expend to form ventricle lateral

29
Q

CSF is produced by

A

plexus coroid

underlies certain part of the ventricle lateral wall

30
Q

how will CSF flow

A

through the ventricle system, spinal corda centre system and subarachnoid channel

31
Q

Holoprosencephaly (HPE)

A

congenital anomaly

incomplete development of the brain

32
Q

how much does the brain weigh at birth

A

400 g

33
Q

when is the most rapid growth of the brain

A

in utero

during 1st 20 prenatal weeks

34
Q

by age 3 the weight of the brain is

A

1200g

almost the weight of an adult brain

slow growth till age 18

35
Q

after age 50 the brain

A

slowly declines in brain size

36
Q

does size of the brain indicate intelligence

A

no

37
Q

when gender has a larger brain

A

male

38
Q

CNS is formed by

A

neural tube

39
Q

PNS is formed by

A

nueral crest

40
Q

what are the first cells to differentiate in the nervous system

A

neuros

communicating cells

41
Q

2nd cells to differentiate in the NS

A

neuroglia

supporting cells

42
Q

when are major divisions of the CNS present

A

4th week after fertilization

43
Q

when does the cerebellum appear

A

later

outgrowth of the brainstem (appears in 4th week of fertilization)