Brain During Development Flashcards

1
Q

what are the last portions of the neural tube to close called

A

anterior and posterior neuropores

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2
Q

when do the last portions of the neural tube close

A

end of the embryonic week

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3
Q

what does the neural tube surround

A

fluid filled central cavity

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4
Q

rostral end of the neural tube

A

larger and more irregular

gives rise to the brain

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5
Q

closure of caudal neruopore

A

corresponds to the upper lumbar segments of the cord

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6
Q

how does the brain develop

A

3 major brain divisions –> occur @ 3/4 week

secondary divisions –> @ 5th week

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7
Q

3 major brain divisions during development

A

prosencephalon (forebrain)

mesencephalon (midbrain)

rhombencephalon (hindbrain)

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8
Q

secondary divisions –> prosencephalon

A

telencephalon

diencephalon

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9
Q

secondary divisions –> rhombencephalon

A

metencephalon

myelencephalon

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10
Q

rhombencephalon –> myelencephalon –> mature brain?

A

medulla oblangata

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11
Q

rhombencephalon –> metencephalon –> mature brain?

A

pons and cerebellum

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12
Q

mesencephalon –> mature brain?

A

midbrain

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13
Q

prosencephalon –> diencephalon –> mature brain?

A

thalamus

epithalamus

hypothalamus

subthalamus

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14
Q

prosencephalon –> telencephalon–> mature brain?

A

cerebral hemispheres

corpus striatum

cerebral cortex

white matter

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15
Q

slide 60

A

pic

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16
Q

what do flexures do

A

accommodate the shape changes of the brain as it becomes round

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17
Q

different flexures

A

cervical

mesencephalic

pontine

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18
Q

cervical flexure

A

jxn of the rhombencephalon w/ the spinal cord

19
Q

mesencephalic flexure

A

level of the midbrain

20
Q

pontine flexure

A

in the metencephalon

21
Q

when do meninges first appear

A

4th week as single mesodermally derived primary meninx

22
Q

when do fluid-filled spaces appear

A

w/in the primary meninx

1 week later

giving rise to meninges

23
Q

layers of the meninges from inside out

A

pia mater –> arachnoid –> dura mater

24
Q

pia mater

A

closest to nervous tissue

25
arachnoid
interposed b/w the pia and dura mater spiderweb-like
26
dura mater
lines the cranial cavity and the spinal canal
27
what will permeate the CSF
ventricle lateral
28
how does the ventricle lateral develop
neural tube will undergo changes and finally expend to form ventricle lateral
29
CSF is produced by
plexus coroid underlies certain part of the ventricle lateral wall
30
how will CSF flow
through the ventricle system, spinal corda centre system and subarachnoid channel
31
Holoprosencephaly (HPE)
congenital anomaly incomplete development of the brain
32
how much does the brain weigh at birth
400 g
33
when is the most rapid growth of the brain
in utero during 1st 20 prenatal weeks
34
by age 3 the weight of the brain is
1200g almost the weight of an adult brain slow growth till age 18
35
after age 50 the brain
slowly declines in brain size
36
does size of the brain indicate intelligence
no
37
when gender has a larger brain
male
38
CNS is formed by
neural tube
39
PNS is formed by
nueral crest
40
what are the first cells to differentiate in the nervous system
neuros communicating cells
41
2nd cells to differentiate in the NS
neuroglia supporting cells
42
when are major divisions of the CNS present
4th week after fertilization
43
when does the cerebellum appear
later outgrowth of the brainstem (appears in 4th week of fertilization)