Circadian Rhythms Flashcards
How long?
24 hours
Sleep- wake cycle exogenous zeitgebers
Drowsy at nights and alert in the day shows affect of daylight
Sleep-wake cycle endogenous pacemakers
Biological clock with no external stimuli is free-running
Sleep-wake cycle
Basic rhythm governes by superchiasmatic nucleus which is just above the optic chiasm which provides info from eyes about light
Siffre
Free running case study
- 2 months then 6 months living in cave
- lights on when he work up and off when he slepy
- = s/w cycle was 25 hours which was regular
Aschoff and Wever
ppts in bunker for 4 weeks with ni natural light
- all but one (29 hours) have a cycle of 24-25 hours
Folkard et al
12 ppts with no natural light for 4 weeks
- unknown to ppts the clock was sped up so only 22 hours passed
- = ppts could not adjust to pace
- = suggests existence and strength of endogenous pacemakers
Research conclusions
Aschoff and Wever + Siffre
- we have an internal body clock
- absense of exogenous zeitgebers leads to a s/w cycle longer than 24 hours
- exogenous zeitgebers keep our body clock at 24 hours
AO3 + application to medicine
Helps determine best time to administer drugs
- heart attacks common in the early morning so drugs to be taken at night with a slow release
AO3 + application to work
Shift work results in a desynchronised circadian rhythm which has adverse cognitive and psychological affects
- shift work increases risk of heart disease times 3
- economic implications = how best to manage shift work
AO3 - correlation
adverse effects as a result of shift work could be due to the high divorce rates as spend a lot of time away from family
AO3 - case study
ppts may not represent wider population which limits meaningful generalisations