Churg Srauss Syndrome and Granulomatosis with Polyangitis Flashcards

1
Q

What is Churg strauss?

A

pANCA positive small vessel granulomatosis

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2
Q

Typical presentation?

A

Patient presents with new onset chronic rhinitis and asthma. Blood tests show eosinophilia and raised IgE.

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3
Q

What is the triad of symptoms in churg strauss?

A

Rhinitis/asthma

Eosinophilia

Glomerulonephritis

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4
Q

What is granulomatosis with polyangitis?

A

c-ANCA +ve granulomatosis

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5
Q

What is c-ANCA?

A

Antiproteinase c antibody

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6
Q

What is the triad of granulomatosis with polyangitis?

A

URTI
LRTI
Renal impairment (glomerulonephritis)

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7
Q

What skin finding may present with granulomatosis with polyangitis?

A

Pyoderma gangrenosum

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8
Q

What is the treatment for churg strauss and granulomatosis with polyangitis

A

Cyclophosphamide/azothiaprine

+ prednisolone/methylprednisolone

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