Chronic kidney disease: eGFR and classification

Question 1

Chronic kidney disease: eGFR and classification

Answer 1

eGFR: The most commonly used formula is the Modification of Diet in Renal Disease (MDRD) equation, which uses the following variables:
CAGE
-creatinine
-age
-gender
-ethnicity

Factors which may affect the result
-pregnancy
-muscle mass (e.g. amputees, body-builders)
-eating red meat 12 hours prior to the sample being taken

CKD stage
1: Greater than 90 ml/min, with some sign of kidney damage on other tests (if all the kidney tests* are normal, there is no CKD)
2: 60-90 ml/min with some sign of kidney damage (if kidney tests* are normal, there is no CKD)
3a: 45-59 ml/min, a moderate reduction in kidney function
3b: 30-44 ml/min, a moderate reduction in kidney function
4: 15-29 ml/min, a severe reduction in kidney function
5: Less than 15 ml/min, established kidney failure - dialysis or a kidney transplant may be needed