Lung cancer: paraneoplastic features Flashcards

1
Q

Lung cancer: paraneoplastic features

A

Small cell:
-ADH
-ACTH - not typical, hypertension, hyperglycaemia, hypokalaemia, alkalosis and muscle weakness are more common than buffalo hump etc
-Lambert-Eaton syndrome

Squamous cell:
-Hypercalcaemia due to (PTH-rp) parathyroid hormone-related protein secretion causing
-Hyperthyroidism due to ectopic TSH
-Hypertrophic pulmonary osteoarthropathy (HPOA)
-Clubbing

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