Chronic Kidney Disease (CKD) Flashcards
Chronic Kidney Disease (CKD) occurs with a GFR of _____ for ______?
- <60 mL/min for 3 months or longer
End-Stage Renal Disease (ESRD) occurs when a GFR of?
< 15
GFR for the stages of CKD?
1) 90 or greater
2) 60 - 89
3) 30 - 59
4) 15-29
5) < 15
Leading causes of CKD?
- Diabetes (50%)
- HTN (25%)
Risk Factors for CKD?
- Diabetes (50%)
- HTN (25%)
- Age
- Obesity
- Health Disparities
Clinical Manifestations of CKD/Uremia - GI?
anorexia, N/V, bleeding, gastritis
Clinical Manifestations of CKD/Uremia -Endocrine/Reprodutive
hyperparathyroidism, thyroid abnormalities, amenorrhea, ED
Clinical Manifestations of CKD/Uremia - Hematologic?
anemia, bleeding, infection
Clinical Manifestations of CKD/Uremia -Pulmonary/
pulmonary edema, uremic pleuritis, pneumonia
Metabolic Complications of CKD?
- Waste product accumulation
- As GFR ↓, BUN ↑ , creatinine levels ↑
- Altered carbohydrate metabolism
- ↑ triglycerides
Electrolyte/Acid-Base Imbalances of CKD?
- Metabolic Acidosis
- Hyperkalemia
- Hypermagnesemia
- Sodium – normal or altered
GFR is base on what factors?
age, creatinine, gender and race
CKD Diagnostic Studies?
- H &P
- Urine
- dipstick: +protein >2x in 3 months
- Albumin-to-creatinine ratio elevated
- use first void
- GFR
- Renal ultrasound
- Renal biopsy
What is the goal for BP in a patient with CKD?
130/80
Why does CKD cause anemia?
impaired production of erythropoietin by the kidneys