Chronic Inflammatory Skin Conditions Flashcards
What is this?
Psoriasis - Plaque psoriasis
What is the pathophysiology behind psoriasis?
Chronic inflammation the skin and hyperproliferation of the keratonocytes with the inflammation
What are some precipitating factors for psoriasis?
Trauma
Infection
Drugs/Alcohol
Stress
What are the types of psoriasis?
- Chronic plaque - Most common extensor surfaces
- Seborrhoeic - Nasal folds
- Flexural (Inverse)
- Guttate - drop shaped and salmon pink
- Pustular
- Erythrodermic
What are the common symptoms of psoriasis including the appearence of the rash
Appearence - Well demarcated erythematous plaque that is scaly
Symptoms - Itchy, burning, painful and may bleed
What are some systemic symptoms of psoriasis?
Psoriatic arthropathy
Onycholyis
Pitted nails
What are five treament methods for psoriasis?
- Education - not malignancy/infection, avoid triggers
- Topical emolients and steroids to maintain barrier and reduce inflammation
- Vitamin D/Retinoids - slow keratinocyte production
- Phototherapy - reduce inflammation in extensive disease
- Systemic immunosuppresants if needed eg methotrexate
What is this?
Eczema/Dermatitis
What is this?
Eczema/Dermatitis
What is atopic eczema?
This is ezcema that appears during childhood and normally clears by teenage years but can remerge.
Atopic means sensitive to things
What is the pathophysiology behind eczema and what can cause it?
It is a skin barrier dysfunction characterised by HIGH IGE where the body attempts to fight causes which leads to the symptoms.
Causes:
- Heat
- Food
- Allergens
- Stress
- Infection
- etc
What does an ezcema rash look like?
Erythemtous, dry, scaly
Where does eczema commonly appear?
Face or extensors of infants
Flexors of children adults
What does it have to be to be ezcema?
ITCHY
What happens from chronic itching of eczema?
Lichenification