Chronic Inflammation Flashcards

1
Q

What are the main inflammatory cells involved in chronic inflammation?

A

Lymphocytes, plasma cells, and macrophages

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2
Q

What are the consequences of a fibrous gall bladder? (Chronic cholesystitis)

A

1) Non-contractile in response to stimuli
2) Fatty food intolerance
3) Right upper quadrant pain

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3
Q

Damaged smooth muscle cannot heal by ….. But can heal by ……which results in …..

A

1) Regeneration
2) Repair
3) Fibrous scarring

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4
Q

What are macrophages derived from? And what do they do?

A

1) Circulating monocytes

2) Phagocytosis and immune surveillance

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5
Q

Macrophages specific to the liver are called?

A

Kupffer cells

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6
Q

What is a granuloma?

A

An aggregate of macrophages. It is a sub-type of chronic inflammation.

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7
Q

What do repeated episodes cycles of ulceration/regeneration induce?

A

Pre-malignant changes (dysplasia)

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