Chronic inflammation

Question 1

Prolonged inflammation consisting of active inflammation and tissue destruction

Answer 1

Chronic inflammation

Question 2

Cause of Chronic inflammation

Answer 2

• persistent microbial infection
• prolonged exposure to infection
• Autoimmune system

Question 3

Cells involved in Chronic inflammation

Answer 3

• macrophage

- lymphocytes

Question 4

collection of ephiteloid histocytes and are multinucleated giant cells

Answer 4

Granulomatous inflammation

Question 5

prevent the spread of diseases

Answer 5

Epitheloid discocytes

Question 6

Causes of Immune Cells

Answer 6

Mycobacterium, Fungi, Histoplasma capsulatum, Blastomyces dermatitis, Foreign material, Sarcoidis, Silica

Question 7

Involves regeneration of the parenchyma or replacement of damaged tissue with a scar if regeneration is not possible

Answer 7

Repair

Question 8

Regeneration of cells combined with scarring and fibrosis

Answer 8

Healing

Question 9

Process of healing

Answer 9

Induction of inflammatory process
Act to contain damage
Removal of infecting substance
Start deposition of ECM
Formation of new blood vessels
Production of ECM, collagen
tissue remodeling
wound contracture
increasing wound strength
2 months- 75% of skin regained

Question 10

4 processes:

Answer 10

• formation of new blood vessels
• Proliferation of fibroblasts
• deposition of ECM
• Maturation and recognization of tissue and fibers

Question 11

how many hours do process of scarring begins?

Answer 11

within 24 hours of onset of acute inflammation

Question 12

in how many days do granulation tissue formed?

Answer 12

3-5 days

Question 13

what are absent in week 2 in time frame of scarring

Answer 13

Edema and inflammatory cells

Question 14

Healing by First intention, wound that has

Answer 14

• clean edges
• close approximation of margins
• minimal tissue disruption

Question 15

act as scavengers

Answer 15

PNS

Question 16

Granulation tissue composed of

Answer 16

• macrophage
• blood vessels
• fibroblast

Question 17

Healing by 2nd intention:

Answer 17

• unclean edges
• extensive tissue disruption
• tissue necrosis

Question 18

factors that may impair the process of wound healing:

Answer 18

• infection
• nutritional deficiency
• glucocorticoid therapy
• result in decrease fibrosis

Question 19

unintentional reopening of the wound to pressure or torsion

Answer 19

dehiscence

Question 20

decrease amount of blood available

Answer 20

poor perfusion

Question 21

blockage of artery for blood supply to flow properly

Answer 21

amphelodenopathy

Question 22

complications of wound healing:

Answer 22

• inadequate healing

- excessive scar formation