chronic inflammation Flashcards
what is chronic inflammation
a long term reaction an inflammatory stimulus, accompanied by tissue injury due to sustained inflammatory response
what cells are involved in chronic inflammation
monocytes and lymphocytes
how long may chronic inflammation last
weeks - lifetime
what is the nature of chronic inflammation
theres changes to wound healing
- proliferation of fibroblasts + small blood vessels
what cell is most important in chronic inflammatory responses
macrophages
what is the role of M1 and M2 macrophages in chronic inflammatory environment
they regulate it
what is granulomatous inflammation
when immune cells clump together at the site of infection/inflammation
- to contain the area and prevent it from spreading