antigen presentation Flashcards
what is the difference between MHC and HLA
nothing. they are the same lol
what does MHC stand for
major histocompatibility complex
what does HLA stand for
human leukocyte antigen
what sort of cells express MHC class 1
most cells apart from neurones
what sort of cells express MHC class II
antigen presenting cells
what type of MHC binds to CD8 receptors
MHC class I
cytotoxic T-cells
what type of MHC binds to CD4 receptors + what type of T-cells do this
MHC class II
helper T-cells
what are self peptides
recognisable short peptide chains
what happens when CD8 + cytotoxic T-cells are bound to MHC class I
infected cell is killed
what happens when CD4 + T-helper cells are bound to MHC class II -antigen presenting cells
help is provided on B=cells
how are lymph nodes involved with antigens
receive lymphoid cells and antigens from the blood + they are concentrated in lymph nodes
how do dendritic cells obtain antigens
phagocytosis