Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

GI > Chron's Disease* > Flashcards

Chron's Disease* Flashcards

1
Q

What is Crohn’s

A

Chronic Inflammatory bowel disease characterised by Transmural granulomatous inflammation in the GI tract (Rectum spared)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the most common age of onset for Crohn’s

A

15 to 40 year old

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What group of people are more prone to Crohn’s

A

Caucasian and Jews

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the chance of familial Crohn’s

A

10-25% chance Crohn’s is passed on

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the symptoms of Crohn’s

A

Abdominal cramp
Weight loss
fever
RUQ pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the signs of Crohn’s

A

Anaemia - clubbing and pale
Apthous ulcers
Tender right Iliac fossa
Do PR exam - fistulae and perianal abscess

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the DERM manifestations of Crohn’s

A

Erethyma nodosum

Pyoderma gangrenosum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the eye manifestations of Crohn’s

A

Anterior uveitis

Episcleritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the MSK manifestations of Crohn’s

A

Arthritis

Sacro-ilitis (like Ankylosing)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What type of stones can Crohn’s cause

A

Gall stones (common>UC)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the investigations of Crohn’s

A

pANCA Negative
Raised Faecal Calcoprotein (IBD)
Endoscopy = Skip lesion, Cobblestone and string sign
Biopsy = Transmural inflammation w/ non caseasting granuloma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the string sign of Kantour (GI series)

A

String like terminal ileum found in Crohn’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What will Bloods show in Crohn’s

A 
Raised WCC
Raised ESR/CRP
Raised Platelets (Thrombocytosis)
Anaemia (Chronic)
Low albumin (malabsorption)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is faecal calcoprotein

A

An antigen of neutrophils and is raised with inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the gold standard investigation for CROHN’S

A

Colonoscopy

  • Rose thorn ulcer(transmural granulomatous inflammation)
  • Skip lesions (Intermittent inflammation)
  • Cobblestone mucosa (erythema nodosum)
  • Non caseating granuloma
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How would you medically treat Crohn’s flare

A

Sulasalazine and Prednisolone

17
Q

What should be given to patients with severe Crohn’s and don’t respond to remission

A

Biological agents (Anti TNF antibodies)

  • Infliximab
  • Adalimumab
18
Q

How would you maintain remission of Crohn’s

A 
Ist = Azathioprine
2nd = Methotrexate
19
Q

How would you manage a peri-anal fistula

A

High fistula = Drainage Seton
Low fistula = Fistulotomy
Sphincter saving = fibrin glue and plug

20
Q

How would you manage a peri anal abscess

A

IV antibiotics

Incision and Drainage

21
Q

What is Pellagra( DDD)

A

A patient with Chron’s can present with DDD due to malnutrution

  • DEMENTIA
  • DERMATITIS
  • DIARRHOEA
22
Q

After a bowel resection, What is a possible diagnosis causing steatorrhea

A

short bowel syndrome

23
Q

What is a complication of TPN (Total parenteral nutrition)

A

Hypophospahatemia/magnesia

  • SOB
  • Seizure
24
Q

How would you differentiate the inflammation between Chrons and UC

A 
Crohn's = Transmural
UC = Mucosa confined

GI (15 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions