Chromosomal Variation Flashcards
1
Q
Reverse Duplication
A
- Duplication of a chromosome segment in which the sequence of the duplicated segment is inverted relative to the sequence of the original segment.
2
Q
Segmental Duplication
A
- Duplicated chromosome segments larger than 1000 bp.
3
Q
Karyotype
A
- The complete set of chromosomes possessed by an organism; usually presented as a picture of a complete set of its metaphase chromosomes and arranged by length (longest to shortest).
4
Q
Tandem Duplication
A
- Chromosome rearrangement in which a duplicated chromosome segment is adjacent to the original segment.
5
Q
Displaced Duplication
A
- Chromosome rearrangement in which the duplicated segment is some distance from the original segment, either on the same chromosome or on a different one.
6
Q
Chromosome Duplication
A
- Mutation that doubles a segment of a chromosome.
7
Q
Chromosome Rearrangement
A
- Chromosome mutations that change the structures of individual chromosomes.
8
Q
Chromosome Mutation
A
- Variations in the number and structure of chromosomes; often affects many genes and has large phenotypic effects.
9
Q
Paracentric Inversion
A
- Chromosome inversion that does not include the centromere in the inverted region.
10
Q
Chromosome Inversion
A
- Rearrangement in which a segment of a chromosome has been inverted 180 degrees.
11
Q
Chromosome Deletion
A
- Loss of a chromosome segment.
12
Q
Dicentric Chromatid
A
- Chromatid that has two centromeres; produced when crossing over takes place within a paracentric inversion. The two centromeres of the dicentric chromatid are frequently pulled toward opposite poles in mitosis or meiosis, breaking the chromosome.
13
Q
Pericentric Inversion
A
- Chromosome inversion that includes the centromere in the inverted region.
14
Q
Acentric Chromatid
A
- Chromatid that lacks a centromere; produced when crossing over takes place within a paracentric inversion. The acentric chromatid does not attach to a spindle microtubule and does not segregate in meiosis or mitosis, so it is usually lost after one or more rounds of cell division.
15
Q
Translocation
A
- Movement of genetic material between nonhomologous chromosomes or within the same chromosome.