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Step Hematology > Chromosomal Translocations > Flashcards

Chromosomal Translocations Flashcards

1
Q

t(8;14)

A

Burkitt lymphoma (c-myc activation)

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2
Q

t(9;22)

A

Philadelphia chromosome - CML (BCL-ABL hybrid, constitutively active tyrosine kinase)

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3
Q

t(11;14)

A

Mantle cell lymphoma (cyclin D1 activation)

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4
Q

t(14;18)

A

Follicular lymphoma (BCL-2 activation)

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5
Q

t(15;17)

A

M3 type of AML, associated in Down Syndrome

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Step Hematology (11 decks)

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