Cholinergic and Adrenergic Drugs Flashcards

1
Q

Phenylephrine

A

Selective Alpha-1 Agonist

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2
Q

Oxymetazoline

A

Selective Alpha-1 Agonist

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3
Q

Naphazoline

A

Selective Alpha-1 Agonist

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4
Q

Clonidine

A

Selective Alpha-2 Agonist (sympatholytic)

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5
Q

Guanfacine

A

Selective Alpha-2 Agonist (sympatholytic)

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6
Q

Fenoldopam

A

Selective DA-1 Agonist

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7
Q

Methyldopa

A

Partial Agonist of Adrenergic Receptors

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8
Q

Phenoxybenzamine

A

Irreversible Non-selective Alpha Antagonist

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9
Q

Phentolamine

A

Reversible non-selective Alpha Antagonist

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10
Q

Prazosin

A

Selective Alpha-1 Antagonist

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11
Q

Terazosin

A

Selective Alpha-1 Antagonist

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12
Q

Ephedrine

A

Stimulate α & β receptors AND release stored NE from nerve terminals

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13
Q

Pseudoephedrine

A

Stimulate α & β receptors AND release stored NE from nerve terminals

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14
Q

Isoproterenol

A

Nonselective Beta-1/2 Agonist

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15
Q

Dobutamine

A

Selective Beta-1 Agonist (B1>B2,A)

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16
Q

Albuterol

A

Selective Beta-2 Agonist (B2>B1)

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17
Q

Metaproterenol

A

Selective Beta-2 Agonist

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18
Q

Terbutaline

A

Selective Beta-2 Agonist

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19
Q

Ritodrine

A

Selective Beta-2 Agonist

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20
Q

Propranolol

A

Nonselective Beta-1/2 Antagonist

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21
Q

Carteolol

A

Nonselective Beta-1/2 Antagonist

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22
Q

Nadolol

A

Nonselective Beta-1/2 Antagonist

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23
Q

Pindolol

A

Nonselective Beta-1/2 Partial Antagonist

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24
Q

Atenolol

A

Selective Beta-1 Antagonist

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25
Q

Metoprolol

A

Selective Beta-1 Antagonist

Beta-arrestin signaling pathway agonist

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26
Q

Bisoprolol

A

Selective Beta-1 Antagonist

Beta-arrestin signaling pathway agonist

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27
Q

Esmolol

A

Short-acting Beta-1 Antagonist

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28
Q

Carvedilol

A

Beta-1/2, Alpha-1 Antagonist

Beta-arrestin signaling pathway agonist

29
Q

Labetalol

A

Beta-1/2, Alpha-1 Antagonist

30
Q

Entacapone

A

Catechol-O-methyltransferase Inhibitor

31
Q

Isocarboxazid

A

Monoamine Oxidase Inhibitor

32
Q

Selegiline

A

Monoamine Oxidase Inhibitor

33
Q

Carbidopa

A

Dopa-decarboxylase Inhibitor

34
Q

Benserazide

A

Dopa-decarboxylase Inhibitor

35
Q

Norepinephrine

A

Alpha-1/2; Beta-1 agonist (A1 > A2 > B1)

36
Q

Epinephrine

A

Alpha-1/2, Beta-1/2 agonist (B>A)

37
Q

Bethanechol

A

Cholinergic agonist

38
Q

Carbachol

A

Cholinergic agonist

39
Q

Methacholine

A

Muscarinic agonist

40
Q

Pilocarpine

A

Cholinergic agonist

41
Q

Galantamine

A

AChE inhibitor

42
Q

Donepezil

A

AChE inhibitor

43
Q

Rivastigmine

A

AChE inhibitor

44
Q

Edroponium

A

AChE inhibitor

45
Q

Neostigmine

A

AChE inhibitor

46
Q

Physostigmine

A

AChE inhibitor (BBB penetration)

47
Q

Pyridostigmine

A

AChE inhibitor

48
Q

Atropine

A

Muscarinic antagonist

49
Q

homatropine

A

Muscarinic antagonist

50
Q

tropicamide

A

Muscarinic antagonist

51
Q

Benztropine

A

Muscarinic antagonist

52
Q

trihexyphenidyl

A

Muscarinic antagonist

53
Q

glycopyrrolate

A

Muscarinic antagonist

54
Q

hyoscyamine

A

Muscarinic antagonist

55
Q

dicyclomine

A

Muscarinic antagonist

56
Q

ipratropium

A

Muscarinic antagonist

57
Q

tiotropium

A

Muscarinic antagonist

58
Q

oxybutynin

A

Muscarinic antagonist

59
Q

solifenacin

A

Muscarinic antagonist

60
Q

tolterodine

A

Muscarinic antagonist

61
Q

scopolamine

A

Muscarinic antagonist

62
Q

Fendolapam

A

D1 agonist

63
Q

isoproterenol

A

Beta agonist (B1=B2)

64
Q

midrodrine

A

alpha-1 agonist

65
Q

Mirabegron

A

B3 agonist

66
Q

mirtazapine

A

Alpha 2 Antagonist

67
Q

acebutolol

A

B1 selective partial agonist

68
Q

nebivolol

A

B1 antagonist, B3 agonist