Cholesterol, lipoproteins, and liver

Question 1

lipids are transported in circulation packaged in

Answer 1

lipoproteins

Question 2

deliver TAG to cells in the body

Answer 2

chylomicrons and VLDL

Question 3

synthesized by enterocytes

Answer 3

chylomicrons

Question 4

VLDL is synthesized by the

Answer 4

liver

Question 5

breaks off TAG from chylomicrons and VLDL

Answer 5

lipoprotein lipase

Question 6

delivers cholesterol to cells in the body

Answer 6

LDL

Question 7

cells take up cholesterol by

Answer 7

receptor-mediated endocytosis

Question 8

HDL is for what type of cholesterol transport?

Answer 8

reverse

Question 9

link between cholesterol and heart disease was recognized through study of

Answer 9

familial hypercholesterolemia

Question 10

lipid levels are outside of normal range is called

Answer 10

dyslipidemia

Question 11

most important drugs for treating dyslipidemia?

Answer 11

statins

Question 12

inhibit HMG-CoA reductase

Answer 12

statins

Question 13

bind to the nuclear receptor PPAR-alpha to increase HDL’s and primarily decrease trigs

Answer 13

fibrates

Question 14

most effective drug for raising HDL

Answer 14

niacin

Question 15

inhibits cholesterol absorption in the SI

Answer 15

ezetimibe