16. Bone and Joint Flashcards
40% of men and 60% of women with RA also have
anemia
3% of cases: leukopenia, splenomegaly, and RA
Felty’s syndrome
85% sensitive for RA
RA factor (RF) which involves immunoglobins
can be ordered along with RF to assess RA severity and prognosis
cyclic citrullinated peptide (CCP)
95% of those with a positive _______ will meet RA criteria in future
CCP antibody
Spine and SI (peripheral j 30%) and ESR elevated in 90%
AS
is HLA-B27 diagnostic of AS?
NO
Psoriatic arthritis invovles
DIP and Spine (20%)
what percent of psoriatics develop Psoriatic arthritis?
10%
50% with chronic Reiter’s also have _____ involvement
spine
hypersensitivity reaction after beta-hemolytic group A strep infection which causes aggregations of histiocytes called Aschoff bodies
Acute Rheumatic Fever (ARF)
Aschoff bodies
Acute Rheumatic Fever (ARF)
ASO titer over 200 indicates
recent strep infection
ASO titer over 500 indicates
Acute Rheumatic Fever (ARF)
is elevated ESR specific for ARF?
NO
how common does gout hit the spine?
RARELY
examples of improper purine metabolism causing gout
increased uptake, decreased excretion, or increased production
most important cause of gout to rule out?
increased production
hyper-metabolic syndromes that cause uric acid to rise?
- Myloprolifertive syndromes
- leukemia
- polycythemia vera
- malignancies
- chemo/radiation
- hemolytic anemia
- diabetes
- sarcoidosis
myalgia/fatigue, headache, stifness
collagen-vascular diseases
important marker for collagen-vascular diseases
Anti Nuclear Antibody (ANA)
list of collagen-vascular diseases
- progressive systemic sclerosis (PSS)
- mixed connective tissue disease (MCTD)
- Sjorgens syndrome
- temporal arteritis
ANA indicates
autoimmune disease
ANA is present 95% in
SLE
and others
