Chlorphenamine

Question 1

What is chlorphenamine

Answer 1

It is an antihistamine (piriton)
It binds to H1 histomine sites
This blocks histomine from binding and therefore reduces the allergic response

Question 2

Indications of chlorphenamine

Answer 2

Symptomatic allergic reactions that are not anaphylactic but just causing patient distress

Alleviating distressing post adrenaline symptoms only after adrenaline is given and pt is stable

Question 3

Presentation of chlorphenamine

Answer 3

Ampules: 10mg in 1ml
Tablet: 4mg of chlorphenamine
Oral solution: 2mg in 5ml

Question 4

Route and dosage of chlorphenamine

Answer 4

10mg/1ml - IV / IM
Adults: 10mg/1m no repeat dosage

Question 5

Contraindications of chlorphenamine

Answer 5

Known hypersensitivity
Pts that have been treated with MAOI (monoamine oxidase inhabitors) in the last 14 days

Question 6

Cautions of chlorphenamine

Answer 6

Pregnancy and breastfeeding
Hypotension
Epilepsy
Glaucoma
Severe liver disease

Question 7

Side effects of chlorphenamine

Answer 7

Dry mouth
Sedation
Headache
Urinary retention
Psychomotor impairment
Gastrointestinal disturbance
Convulsions (rare)